The role of human aldehyde dehydrogenase in normal and cancer stem cells
Normal stem cells and cancer stem cells (CSCs) share similar properties, in that both have
the capacity to self-renew and differentiate into multiple cell types. In both the normal stem …
the capacity to self-renew and differentiate into multiple cell types. In both the normal stem …
Mesenchymal stem cells for the sustained in vivo delivery of bioactive factors
Mesenchymal stem cells (MSC) are a promising tool for cell therapy, either through direct
contribution to the repair of bone, tendon and cartilage or as an adjunct therapy through …
contribution to the repair of bone, tendon and cartilage or as an adjunct therapy through …
Aldehyde dehydrogenase 1 is a tumor stem cell-associated marker in lung cancer
F Jiang, Q Qiu, A Khanna, NW Todd, J Deepak… - Molecular cancer …, 2009 - AACR
Tumor contains small population of cancer stem cells (CSC) that are responsible for its
maintenance and relapse. Analysis of these CSCs may lead to effective prognostic and …
maintenance and relapse. Analysis of these CSCs may lead to effective prognostic and …
High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability
AK Croker, D Goodale, J Chu… - Journal of cellular …, 2009 - Wiley Online Library
Cancer stem cells (CSCs) have recently been identified in leukaemia and solid tumours;
however, the role of CSCs in metastasis remains poorly understood. This dearth of …
however, the role of CSCs in metastasis remains poorly understood. This dearth of …
[HTML][HTML] ALDH1A1 is a marker for malignant prostate stem cells and predictor of prostate cancer patients' outcome
Prostate cancer (PCa) contains a small population of cancer stem cells (CSCs) that
contribute to its initiation and progression. The development of specific markers for …
contribute to its initiation and progression. The development of specific markers for …
Aldehyde dehydrogenase 1 A1–positive cell population is enriched in tumor-initiating cells and associated with progression of bladder cancer
Y Su, Q Qiu, X Zhang, Z Jiang, Q Leng, Z Liu… - … Biomarkers & Prevention, 2010 - AACR
Abstract Aldehyde dehydrogenase 1 A1 (ALDH1A1) has recently been suggested as a
marker for cancer stem or stem-like cancer cells of some human malignancies. The purpose …
marker for cancer stem or stem-like cancer cells of some human malignancies. The purpose …
ALDH1A1 defines invasive cancer stem-like cells and predicts poor prognosis in patients with esophageal squamous cell carcinoma
L Yang, Y Ren, X Yu, F Qian, BSJ Bian, H **ao… - Modern …, 2014 - nature.com
Invasion and metastasis are the major cause of deaths in patients with esophageal cancer.
In this study, we isolated cancer stem-like cells from an esophageal squamous cell …
In this study, we isolated cancer stem-like cells from an esophageal squamous cell …
Enzyme targeting strategies for prevention and treatment of cancer: Implications for cancer therapy
Extensive growth of cancer in humans is a major cause of death. Numerous studies are
being conducted to improve the early diagnosis, prevention, and treatment of cancer. Recent …
being conducted to improve the early diagnosis, prevention, and treatment of cancer. Recent …
COX-2 induces breast cancer stem cells via EP4/PI3K/AKT/NOTCH/WNT axis
M Majumder, X **n, L Liu, E Tutunea-Fatan… - Stem Cells, 2016 - academic.oup.com
Cancer stem-like cells (SLC) resist conventional therapies, necessitating searches for SLC-
specific targets. We established that cyclo-oxygenase (COX)-2 expression promotes human …
specific targets. We established that cyclo-oxygenase (COX)-2 expression promotes human …
Transplant outcomes in mucopolysaccharidoses
VK Prasad, J Kurtzberg - Seminars in hematology, 2010 - Elsevier
The mucopolysaccharidoses (MPSs) are inherited metabolic disorders (IMDs) caused by
single-gene defects leading to progressive cellular accumulation of glycosaminoglycans …
single-gene defects leading to progressive cellular accumulation of glycosaminoglycans …