Greener approaches to organic synthesis using microreactor technology

BP Mason, KE Price, JL Steinbacher… - Chemical …, 2007 - ACS Publications
Recently, microreactor technology has received a great deal of attention. However, most of
the research carried out in this field is concerned with engineering aspects of microreactors …

Computational fluid dynamics for improved bioreactor design and 3D culture

DW Hutmacher, H Singh - Trends in biotechnology, 2008 - cell.com
The complex relationship between the hydrodynamic environment and surrounding tissues
directly impacts on the design and production of clinically useful grafts and implants. Tissue …

The multiparametric effects of hydrodynamic environments on stem cell culture

MA Kinney, CY Sargent, TC McDevitt - Tissue Engineering Part B …, 2011 - liebertpub.com
Stem cells possess the unique capacity to differentiate into many clinically relevant somatic
cell types, making them a promising cell source for tissue engineering applications and …

Computational modelling of cell spreading and tissue regeneration in porous scaffolds

BG Sengers, M Taylor, CP Please, ROC Oreffo - Biomaterials, 2007 - Elsevier
Improved biological and mechanical functionality of musculoskeletal tissue-engineered
constructs is required for clinical application, which can only be achieved by comprehensive …

Clarifying the tooth-derived stem cells behavior in a 3D biomimetic scaffold for bone tissue engineering applications

CL Salgado, CC Barrias, FJM Monteiro - Frontiers in bioengineering …, 2020 - frontiersin.org
Massive amounts of cell are needed for creating tissue engineered 3D constructs, which
often requires culture on scaffolds under dynamic conditions to facilitate nutrients and …

[HTML][HTML] Computational fluid dynamics modeling of cell cultures in bioreactors and its potential for cultivated meat production—A mini-review

FJC Rivera, J Chen - Future Foods, 2022 - Elsevier
Cultivated meat production was developed as a response to the rapidly increasing demand
for meat consumption. Bioreactor designs were adapted from other bioprocesses to account …

Fluid flow and cell proliferation of mesenchymal adipose‐derived stem cells in small‐scale, stirred, single‐use bioreactors

S Kaiser, V Jossen, C Schirmaier, D Eibl… - Chemie Ingenieur …, 2013 - Wiley Online Library
The fluid flow and suspension characteristics inside small‐scale, stirred, single‐use
bioreactors were investigated experimentally and by means of computational fluid dynamics …

Development and characterization of a parallelizable perfusion bioreactor for 3D cell culture

D Egger, M Fischer, A Clementi, V Ribitsch… - Bioengineering, 2017 - mdpi.com
The three dimensional (3D) cultivation of stem cells in dynamic bioreactor systems is
essential in the context of regenerative medicine. Still, there is a lack of bioreactor systems …

Shear bioreactors stimulating chondrocyte regeneration, a systematic review

N Sharifi, AM Gharravi - Inflammation and Regeneration, 2019 - Springer
It is commonly accepted that the mechanical stimuli are important factors in the maintenance
of normal structure and function of the articular cartilage. Despite extensive efforts, the …

Tissue engineering the mandibular condyle

L Wang, MS Detamore - Tissue Engineering, 2007 - liebertpub.com
Tissue engineering provides the revolutionary possibility for curing temporomandibular joint
(TMJ) disorders. Although characterization of the mandibular condyle has been extensively …