T cells express T cell receptors (TCRs) composed of somatically recombined TCRα and
TCRβ chains, which mediate recognition of major histocompatibility complex (MHC)–antigen …

Single-cell T cell and B cell antigen receptor-sequencing data analysis can potentially
perform in-depth assessments of adaptive immune cells that inform on understanding …

The antibody repertoires of individuals and groups have been used to explore disease
states, understand vaccine responses, and drive therapeutic development. The arrival of B …

Here, we report an update of the VDJdb database with a substantial increase in the number
of T-cell receptor (TCR) sequences and their cognate antigens. The update further provides …

Understanding the hallmarks of the immune response to SARS-CoV-2 is critical for fighting
the COVID-19 pandemic. We assessed antibody and T cell reactivity in convalescent COVID …

B cell and T cell receptor repertoires compose the adaptive immune receptor repertoire
(AIRR) of an individual. The AIRR is a unique collection of antigen-specific receptors that …

Assessment of single-cell gene expression (single-cell RNA sequencing) and adaptive
immune receptor (AIR) sequencing (scVDJ-seq) has been invaluable in studying …

Antibodies are proteins that recognize the molecular surfaces of potentially noxious
molecules to mount an adaptive immune response or, in the case of autoimmune diseases …

Abs are immune system proteins that recognize noxious molecules for elimination. Their
sequence diversity and binding versatility have made Abs the primary class of …

The adaptive immune system recognizes antigens via an immense array of antigen-binding
antibodies and T-cell receptors, the immune repertoire. The interrogation of immune …