The phylum Nucleocytoviricota includes the largest and most complex viruses known. These
“giant viruses” have a long evolutionary history that dates back to the early diversification of …

More than a century ago, the term 'virus' was introduced to describe infectious agents that
are invisible by light microscopy and capable of passing through sterilizing filters. In addition …

Virophages are small double stranded DNA (dsDNA) viruses that can only replicate in a host
by co-infecting with another virus. Marine algae are commonly associated with virophage …

Mimivirus, a DNA virus infecting acanthamoeba, was for a long time the largest known virus
both in terms of particle size and gene content. Its genome encodes 979 proteins, including …

Free-living amoebae (FLA) are parasites within both humans and animals causing a wide
range of symptoms and act as hosts of, and vehicles for phylogenetically diverse …

The accidental discovery of the giant virus of amoeba—Acanthamoeba polyphaga mimivirus
(APMV; more commonly known as mimivirus)—in 2003 changed the field of virology …

Rapid, sensitive, and specific virus detection is an important component of clinical
diagnostics. Massively parallel sequencing enables new diagnostic opportunities that …

The third edition of this bestselling text has been rigorously updated to reflect major new
discoveries and concepts since 2011, especially progress due to extensive application of …

A distinct class of infectious agents, the virophages that infect giant viruses of the
Mimiviridae family, has been recently described. Here we report the simultaneous discovery …

Microbes are the oldest and most widespread, phylogenetically and metabolically diverse
life forms on Earth. However, they have been discovered only 334 years ago, and their …