Challenges and recent progress in oral drug delivery systems for biopharmaceuticals
B Homayun, X Lin, HJ Choi - Pharmaceutics, 2019 - mdpi.com
Routes of drug administration and the corresponding physicochemical characteristics of a
given route play significant roles in therapeutic efficacy and short term/long term biological …
given route play significant roles in therapeutic efficacy and short term/long term biological …
Microfluidic formulation of nanoparticles for biomedical applications
SJ Shepherd, D Issadore, MJ Mitchell - Biomaterials, 2021 - Elsevier
Nanomedicine has made significant advances in clinical applications since the late-20th
century, in part due to its distinct advantages in biocompatibility, potency, and novel …
century, in part due to its distinct advantages in biocompatibility, potency, and novel …
Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines
SJ Shepherd, X Han, AJ Mukalel… - Proceedings of the …, 2023 - National Acad Sciences
Lipid nanoparticles (LNPs) are a potent delivery technology that have made it possible for
the recent clinical breakthroughs in mRNA therapeutics and vaccines. A key challenge to the …
the recent clinical breakthroughs in mRNA therapeutics and vaccines. A key challenge to the …
Synthesis of micro and nanostructures in microfluidic systems
In this critical review, we present an overview of the current progress in synthesis of micro
and nanostructures by using microfluidics techniques. Emphasis is placed on processes that …
and nanostructures by using microfluidics techniques. Emphasis is placed on processes that …
[HTML][HTML] Designer emulsions using microfluidics
We describe new developments for the controlled fabrication of monodisperse emulsions
using microfluidics. We use glass capillary devices to generate single, double, and higher …
using microfluidics. We use glass capillary devices to generate single, double, and higher …
Clogging of microfluidic systems
E Dressaire, A Sauret - Soft matter, 2017 - pubs.rsc.org
The transport of suspensions of microparticles in confined environments is associated with
complex phenomena at the interface of fluid mechanics and soft matter. Indeed, the …
complex phenomena at the interface of fluid mechanics and soft matter. Indeed, the …
Clogging transition of many-particle systems flowing through bottlenecks
When a large set of discrete bodies passes through a bottleneck, the flow may become
intermittent due to the development of clogs that obstruct the constriction. Clogging is …
intermittent due to the development of clogs that obstruct the constriction. Clogging is …
Clogging of noncohesive suspension flows
When flowing through narrow channels or constrictions, many-body systems exhibit various
flowing patterns, yet they can also get stuck. In many of these systems, the flowing elements …
flowing patterns, yet they can also get stuck. In many of these systems, the flowing elements …
Nanoemulsions: the properties, methods of preparation and promising applications
MY Koroleva, EV Yurtov - Russian Chemical Reviews, 2012 - iopscience.iop.org
The properties of nanoemulsions and various methods for their preparation including the
high-energy and low-energy emulsification methods and the combined methods are …
high-energy and low-energy emulsification methods and the combined methods are …
Multiscale dynamics of colloidal deposition and erosion in porous media
Diverse processes—eg, environmental pollution, groundwater remediation, oil recovery,
filtration, and drug delivery—involve the transport of colloidal particles in porous media …
filtration, and drug delivery—involve the transport of colloidal particles in porous media …