Breathing is an essential behavior that presents a unique opportunity to understand how the
nervous system functions normally, how it balances inherent robustness with a highly …

Biochemical and functional studies of ion channels have shown that many of these integral
membrane proteins form macromolecular signaling complexes by physically associating …

The preBötzinger Complex (preBötC), a medullary network critical for breathing, relies on
excitatory interneurons to generate the inspiratory rhythm. Yet, half of preBötC neurons are …

Abstract The large-conductance, Ca 2+-and voltage-activated K+(BK) channel is
ubiquitously expressed in mammalian tissues and displays diverse biophysical or …

The neural mechanisms generating rhythmic bursting activity in the mammalian brainstem,
particularly in the pre‐B ötzinger complex (pre‐B öt C), which is involved in respiratory …

Congenital central hypoventilation syndrome (CCHS) is a genetic disorder of
neurodevelopment, with an autosomal dominant transmission, caused by heterozygous …

The cellular mechanisms underlying pathological alcohol seeking remain poorly
understood. Here, we show an enhancement of nucleus accumbens (NAcb) core action …

Inflammation has been linked to the induction of apneas and Sudden Infant Death
Syndrome, whereas proinflammatory mediators inhibit breathing when applied peripherally …

Small conductance (SK) channels are calcium-activated potassium channels that, when
cloned in 1996, were thought solely to contribute to the afterhyperpolarisation that follows …

Respiratory brainstem neurons fulfill critical roles in controlling breathing: they generate the
activity patterns for breathing and contribute to various sensory responses including …