The Actinobacteria phylum is one of the oldest bacterial phyla that have a significant role in
medicine and biotechnology. There are a lot of genera in this phylum that are causing …

The cloning of five DNA segments carrying at least seven genes (fms1, fms3, fms4, fms5,
fms7, fms11, and fms12) that participate in fortimicin A (astromicin) biosynthesis was …

We have cloned the seven genes that are responsible for biosynthesis of the antibiotic
fortimicin A (FTM A) using a recently developed self-cloning system that employs the …

Micromonospora olivasterospora, a fortimicin A (FTM A, astromicin) producer, was found to
carry an enzyme that converts FTM A to N-formimidoyl FTM A (FI-FTM A). This enzyme (FI …

A highly efficient gene-cloning system for Micromonospora olivasterospora, a producer of
the antibiotic fortimicin A (astromicin), suited to shotgun cloning has been developed. The …

The sisomicin-gentamicin resistance methylase gene (sgm) from Micromonospora zionensis
(the producer of antibiotic G-52 [6-N-methyl-sisomicin]) encodes an enzyme that modifies …

During the last 25 years the isolation and characterization of gene clusters involved in the
biosynthesis of actinomycete secondary metabolites has permitted the elucidation of the …

CaCO3 1.0 g, FeSO4-7H2O 40mg, soy bean meal (" Esusanmito"; A**omoto Co.) 7.5 g and
Bactoagar (Difco) 22g, per liter of deionized water was subsequently incubated in 172F …

The sisomicin-gentamicin resistance methylase {sgm) gene from Micromonospora zionensis
(producer of G-52 antibiotic), encodes an enzyme that modifies 16S rRNA, and thereby …

Two vectors for Micromonospora melanosporea have been constructed with the
Streptomyces plasmid pIJ702 along with the sgm gene (sisomicin-gentamicin resistance …