Role of perivascular cells in kidney homeostasis, inflammation, repair and fibrosis

S Tanaka, D Portilla, MD Okusa - Nature Reviews Nephrology, 2023‏ - nature.com
Perivascular niches in the kidney comprise heterogeneous cell populations, including
pericytes and fibroblasts, with distinct functions. These perivascular cells have crucial roles …

Versatile subtypes of pericytes and their roles in spinal cord injury repair, bone development and repair

S Zhu, M Chen, Y Ying, Q Wu, Z Huang, W Ni, X Wang… - Bone Research, 2022‏ - nature.com
Vascular regeneration is a challenging topic in tissue repair. As one of the important
components of the neurovascular unit (NVU), pericytes play an essential role in the …

Pericytes in the renal vasculature: roles in health and disease

I Shaw, S Rider, J Mullins, J Hughes… - Nature Reviews …, 2018‏ - nature.com
In the dense circulatory system of the kidney, as in all vascularized tissues, pericytes enwrap
capillaries and microvessels to regulate angiogenesis, stabilize microvascular networks and …

Defining human mesenchymal and epithelial heterogeneity in response to oral inflammatory disease

AJ Caetano, V Yianni, A Volponi, V Booth… - Elife, 2021‏ - elifesciences.org
Human oral soft tissues provide the first barrier of defence against chronic inflammatory
disease and hold a remarkable scarless wounding phenotype. Tissue homeostasis requires …

Human perivascular stem cell-derived extracellular vesicles mediate bone repair

J Xu, Y Wang, CY Hsu, Y Gao, CA Meyers, L Chang… - Elife, 2019‏ - elifesciences.org
The vascular wall is a source of progenitor cells that are able to induce skeletal repair,
primarily by paracrine mechanisms. Here, the paracrine role of extracellular vesicles (EVs) …

Enrichment of CD146+ adipose-derived stem cells in combination with articular cartilage extracellular matrix scaffold promotes cartilage regeneration

X Li, W Guo, K Zha, X **g, M Wang, Y Zhang… - …, 2019‏ - pmc.ncbi.nlm.nih.gov
Heterogeneity of mesenchymal stem cells (MSCs) influences the cell therapy outcome and
the application in tissue engineering. Also, the application of subpopulations of MSCs in …

Specific lipid magnetic sphere sorted CD146-positive bone marrow mesenchymal stem cells can better promote articular cartilage damage repair

H Ren, L Zhang, X Zhang, C Yi, L Wu - BMC Musculoskeletal Disorders, 2024‏ - Springer
Background The characteristics and therapeutic potential of subtypes of bone marrow
mesenchymal stem cells (BMSCs) are largely unknown. Also, the application of …

Perivascular mesenchymal progenitors for bone regeneration

AW James, B Péault - Journal of Orthopaedic Research®, 2019‏ - Wiley Online Library
Mesenchymal progenitor cells reside in all assayed vascularized tissues, and are broadly
conceptualized to participate in homeostasis/renewal and repair. The application of …

Comparison of skeletal and soft tissue pericytes identifies CXCR4+ bone forming mural cells in human tissues

J Xu, D Li, CY Hsu, Y Tian, L Zhang, Y Wang… - Bone research, 2020‏ - nature.com
Human osteogenic progenitors are not precisely defined, being primarily studied as
heterogeneous multipotent cell populations and termed mesenchymal stem cells (MSCs) …

[HTML][HTML] The Therapeutic Potential of Pericytes in Bone Tissue Regeneration

A Issabekova, G Kudaibergen, A Sekenova, A Dairov… - Biomedicines, 2023‏ - mdpi.com
Pericytes, as perivascular cells, are present in all vascularized organs and tissues, and they
actively interact with endothelial cells in capillaries and microvessels. Their involvement …