Obesity is a multifactorial disease that continues to increase in prevalence worldwide.
Emerging evidence has shown that the development of obesity may be influenced by …

Obesity remains a significant global health challenge, with bariatric surgery remaining as
one of the most effective treatments for severe obesity and its related comorbidities. This …

Leucine restriction (LR) improves insulin resistance and promotes white adipose tissue
browning. However, the effect of LR on obesity-associated cognitive impairment remains …

The birth, maturation, and integration of new neurons in the adult hippocampus regulates
specific learning and memory processes, responses to stress, and antidepressant treatment …

Consuming a high-fat diet (HFD) is widely recognized to cause obesity and result in chronic
brain inflammation that impairs cognitive function. Repetitive transcranial magnetic …

Augmentation of endoplasmic reticulum (ER) stress may trigger excessive oxidative stress,
which induces mitochondrial dysfunction. The fatty acid amide hydrolase inhibitor, URB597 …

Dentate gyrus of the hippocampus continuously gives rise to new neurons, namely, adult-
born granule cells, which contribute to conferring plasticity to the mature brain throughout …

The short-chain fatty acids (SCFAs) acetate, propionate and butyrate, the major products of
intestinal microbial fermentation of dietary fibres, are involved in fine-tuning brain functions …

Cognition underpins the flexibility of human eating and disruption to higher cognitive
processes, such as inhibitory control and memory, and can result in increased food intake …

Abstract Background The Mediterranean diet (MedDiet) has demonstrated efficacy in
preventing age-related cognitive decline and modulating plasma concentrations of …