Early-life interactions between the microbiota and immune system: impact on immune system development and atopic disease

K Donald, BB Finlay - Nature Reviews Immunology, 2023‏ - nature.com
Prenatal and early postnatal life represent key periods of immune system development. In
addition to genetics and host biology, environment has a large and irreversible role in the …

Distinct spatial and temporal roles for Th1, Th2, and Th17 cells in asthma

W Luo, J Hu, W Xu, J Dong - Frontiers in Immunology, 2022‏ - frontiersin.org
Immune response in the asthmatic respiratory tract is mainly driven by CD4+ T helper (Th)
cells, represented by Th1, Th2, and Th17 cells, especially Th2 cells. Asthma is a …

The varying effects of antibiotics on gut microbiota

L Yang, O Ba**ka, PO Jarju, Y Tan, AM Taal… - AMB express, 2021‏ - Springer
Antibiotics are lifesaving therapeutic drugs that have been used by human for decades.
They are used both in the fight against bacterial pathogens for both human and for animal …

Lung-brain axis

O Ba**ka, L Simbilyabo, Y Tan, J Jabang… - Critical reviews in …, 2022‏ - Taylor & Francis
The appreciation of human microbiome is gaining strong grounds in biomedical research. In
addition to gut-brain axis, is the lung-brain axis, which is hypothesised to link pulmonary …

[HTML][HTML] Neutrophils and asthma

A Yamasaki, R Okazaki, T Harada - Diagnostics, 2022‏ - mdpi.com
Although eosinophilic inflammation is characteristic of asthma pathogenesis, neutrophilic
inflammation is also marked, and eosinophils and neutrophils can coexist in some cases …

Extrinsic factors influencing gut microbes, the immediate consequences and restoring eubiosis

O Ba**ka, Y Tan, KA Abdelhalim, G Özdemir, X Qiu - Amb Express, 2020‏ - Springer
From the emerging studies, the more diverse the microbial population in the gut, the
healthier the gut. Health benefits are associated with the functional characteristics of these …

[HTML][HTML] TMT-based quantitative proteomics reveals suppression of SLC3A2 and ATP1A3 expression contributes to the inhibitory role of acupuncture on airway …

W Tang, M Dong, F Teng, J Cui, X Zhu, W Wang… - Biomedicine & …, 2021‏ - Elsevier
Highlights•Acupuncture was effective in attenuation of AHR, mucus secretion and airway
inflammation in OVA-induced mouse asthma model.•Suppression of SLC3A2 and ATP1A3 …

The influence of asthma on neuroinflammation and neurodevelopment: from epidemiology to basic models

JM Tamayo, HC Osman, JJ Schwartzer… - Brain, Behavior, and …, 2024‏ - Elsevier
Asthma is a highly heterogeneous inflammatory disease that can have a significant effect on
both the respiratory system and central nervous system. Population based studies and …

The role of dendritic cells in allergic diseases

P Liu, C Kang, J Zhang, Y Liu, J Liu, T Hu… - International …, 2022‏ - Elsevier
Allergic diseases are important diseases that affect many patients worldwide. Over the past
few decades, the incidence of allergic diseases has increased significantly due to social …

The gut microbiota pathway mechanisms of diabetes

O Ba**ka, Y Tan, A Darboe, IG Ighaede-Edwards… - AMB Express, 2023‏ - Springer
The contribution of dysbiotic gut microbiota configuration is essential when making
reference to the metabolic disorders by increasing energy. It is important to understand that …