[HTML][HTML] Annexins: from structure to function

V Gerke, SE Moss - Physiological reviews, 2002 - journals.physiology.org
Annexins are Ca 2+ and phospholipid binding proteins forming an evolutionary conserved
multigene family with members of the family being expressed throughout animal and plant …

Annexins: linking Ca2+ signalling to membrane dynamics

V Gerke, CE Creutz, SE Moss - Nature reviews Molecular cell biology, 2005 - nature.com
Eukaryotic cells contain various Ca2+-effector proteins that mediate cellular responses to
changes in intracellular Ca2+ levels. A unique class of these proteins—annexins—can bind …

Intracellular and extracellular roles of S100 proteins

R Donato - Microscopy research and technique, 2003 - Wiley Online Library
S100, a multigenic family of non‐ubiquitous Ca2+‐modulated proteins of the EF‐hand type
expressed in vertebrates exclusively, has been implicated in intracellular and extracellular …

Annexin A2 heterotetramer: structure and function

A Bharadwaj, M Bydoun, R Holloway… - International journal of …, 2013 - mdpi.com
Annexin A2 is a pleiotropic calcium-and anionic phospholipid-binding protein that exists as
a monomer and as a heterotetrameric complex with the plasminogen receptor protein …

Annexins–unique membrane binding proteins with diverse functions

U Rescher, V Gerke - Journal of cell science, 2004 - journals.biologists.com
Annexins are a well-known multigene family of Ca2+-regulated phospholipid-binding and
membrane-binding proteins. Recent work employing annexin-knockdown or-knockout …

The annexins

SE Moss, RO Morgan - Genome biology, 2004 - Springer
Annexins are traditionally thought of as calcium-dependent phospholipid-binding proteins,
but recent work suggests a more complex set of functions. More than a thousand proteins of …

[HTML][HTML] Protein phosphorylation and its role in the regulation of Annexin A2 function

AK Grindheim, J Saraste, A Vedeler - Biochimica et Biophysica Acta (BBA) …, 2017 - Elsevier
Abstract Background Annexin A2 (AnxA2) is a multifunctional protein involved in
endocytosis, exocytosis, membrane domain organisation, actin remodelling, signal …

Annexin A2: The diversity of pathological effects in tumorigenesis and immune response

Y Huang, M Jia, X Yang, H Han, G Hou… - … Journal of Cancer, 2022 - Wiley Online Library
Abstract Annexin A2 (ANXA2) is widely used as a marker in a variety of tumors. By
regulating multiple signal pathways, ANXA2 promotes the epithelial‐mesenchymal …

Annexins family: insights into their functions and potential role in pathogenesis of sarcoidosis

M Mirsaeidi, S Gidfar, A Vu, D Schraufnagel - Journal of translational …, 2016 - Springer
Annexins are Ca 2+-regulated phospholipid-binding proteins that play an important role in
the cell life cycle, exocytosis, and apoptosis. Annexin A11 is one of the oldest vertebrate …

EphA2–YES1–ANXA2 pathway promotes gastric cancer progression and metastasis

L Mao, W Yuan, K Cai, C Lai, C Huang, Y Xu, S Zhong… - Oncogene, 2021 - nature.com
Erythropoietin-producing hepatocellular receptor A2 (EphA2) is a key member of the
receptor tyrosine kinase (RTK) family, while YES Proto-Oncogene 1 (YES1) is a non …