The vitamin D endocrine system is central to the control of bone and calcium homeostasis.
Thus, alterations in the vitamin D pathway lead to disturbances in mineral metabolism …

Osteoporosis is a common multifactorial disorder of reduced bone mass. The disorder in its
most common form is generalized, affecting the elderly, both sexes, and all racial groups …

Disturbances in mineral and bone metabolism are common in patients with CKD. A large
body of evidence indicates that these derangements are associated with increased mortality …

Background & Aims: The liver plays a central role in vitamin D metabolism. Our aim was to
determine the prevalence and type of vitamin D–parathyroid hormone (PTH) disturbance in …

Persistent secondary hyperparathyroidism after renal transplanation. Background The
persistence of secondary hyperparathyroidism after renal transplantation is frequent and …

Uremic secondary hyperparathyroidism is a multifactorial and complex disease often
present in advanced stages of chronic kidney disease. The accumulation of phosphate, the …

Vitamin D has immunomodulatory, anti-inflammatory, antioxidant, and anti-fibrotic actions
that may impact on the occurrence and outcome of immune-mediated disease. The goals of …

Relative hypoparathyroidism (parathyroid hormone [PTH]≤ 200 pg/mL) is prevalent in
hemodialysis (HD) patients, with unknown pathogenesis and prognosis. Thus, to clarify risk …

A genetic contribution to bone mass determination was first described in the early 70s.
Elucidation of gene contribution to this has since been attempted through studies analyzing …

Chronic kidney disease (CKD) is associated with a mineral and bone disorder (CKD-MBD)
which starts early in the course of the disease and worsens with its progression. The main …