Significance: The selenium-containing Glutathione peroxidases (GPxs) 1–4 protect against
oxidative challenge, inhibit inflammation and oxidant-induced regulated cell death. Recent …

This review covers current knowledge of selenium in the environment, dietary intakes,
metabolism and status, functions in the body, thyroid hormone metabolism, antioxidant …

Cadmium is an environmental pollutant known as endocrine disruptor. Testis is particularly
susceptible to cadmium, and testis injury occurs at high but even low levels of exposure …

Selenium (Se) is a naturally occurring metalloid element, which is essential to human and
other animal health in trace amounts but is harmful in excess. Of all the elements, selenium …

The role of Se and various selenoproteins in male reproductive performance is reviewed.
Development of male reproductive tissue requires an optimal level of Se in testis, and a …

The family of glutathione peroxidases comprises four distinct mammalian selenoproteins.
The classical enzyme (cGPx) is ubiquitously distributed. According to animal, cell culture …

The selenoprotein phospholipid hydroperoxide glutathione peroxidase (PHGPx) changes its
physical characteristics and biological functions during sperm maturation. PHGPx exists as a …

Selenium (Se) deficiency or excess impairs testicular development and spermatogenesis,
while the underlying mechanisms in this regard remain unclear. This study was designed to …

Selenoprotein P (Sepp1) is a secreted protein that is made up of 2 domains. The larger N-
terminal domain contains 1 selenocysteine residue in a redox motif and the smaller C …

Recent identification of new selenocysteine-containing proteins has revealed relationships
between the two trace elements selenium (Se) and iodine and the hormone network …