[HTML][HTML] Moxidectin and the avermectins: consanguinity but not identity
The avermectins and milbemycins contain a common macrocyclic lactone (ML) ring, but are
fermentation products of different organisms. The principal structural difference is that …
fermentation products of different organisms. The principal structural difference is that …
[HTML][HTML] Perspectives on the utility of moxidectin for the control of parasitic nematodes in the face of develo** anthelmintic resistance
Macrocyclic lactone (ML) anthelmintics are the most important class of anthelmintics
because of our high dependence on them for the control of nematode parasites and some …
because of our high dependence on them for the control of nematode parasites and some …
The pharmacokinetics and metabolism of ivermectin in domestic animal species
The pharmacokinetic properties of drugs are closely related to their pharmacological
efficacy. The kinetics of ivermectin are characterised, in general terms, by a slow absorption …
efficacy. The kinetics of ivermectin are characterised, in general terms, by a slow absorption …
Comparative distribution of ivermectin and doramectin to parasite location tissues in cattle
Pharmacokinetic studies have been used traditionally to characterize drug concentration
profiles achieved in the bloodstream. However, endectocide molecules exert their persistent …
profiles achieved in the bloodstream. However, endectocide molecules exert their persistent …
First report of a Rhipicephalus microplus tick population multi-resistant to acaricides and ivermectin in the Mexican tropics
A Fernández-Salas, RI Rodríguez-Vivas… - Veterinary …, 2012 - Elsevier
We document the presence of a Rhipicephalus microplus tick population resistant to
acaricides (organophosphates (OP), synthetic pyrethroids (SP), amitraz) and macrocyclic …
acaricides (organophosphates (OP), synthetic pyrethroids (SP), amitraz) and macrocyclic …
Rhipicephalus(Boophilus) microplus resistant to acaricides and ivermectin in cattle farms of Mexico
Ticks and the diseases they transmit cause great economic losses to livestock in tropical
countries. Non-chemical control alternatives include the use of resistant cattle breeds …
countries. Non-chemical control alternatives include the use of resistant cattle breeds …
[HTML][HTML] Macrocyclic lactones and ectoparasites control in livestock: efficacy, drug resistance and therapeutic challenges
Macrocyclic lactones (MLs) are the cornerstone of parasite control in livestock due to their
broad-spectrum activity against endo (nematodes) and ecto (lice, ticks, mites) parasites …
broad-spectrum activity against endo (nematodes) and ecto (lice, ticks, mites) parasites …
Therapy and prevention for human toxocariasis
For the last four decades, knowledge about human toxocariasis with regard to its
epidemiology, pathophysiology, clinical spectrum, and imaging or laboratory diagnosis has …
epidemiology, pathophysiology, clinical spectrum, and imaging or laboratory diagnosis has …
Review of methodology for the determination of macrocyclic lactone residues in biological matrices
M Danaher, LC Howells, SRH Crooks… - … of Chromatography B, 2006 - Elsevier
The macrocyclic lactones (MLs) are probably the anti-parasitic agents most widely used in
the treatment of food producing animals, poultry, aquaculture and crops. Ivermectin was the …
the treatment of food producing animals, poultry, aquaculture and crops. Ivermectin was the …
Preclinical study of single-dose moxidectin, a new oral treatment for scabies: efficacy, safety, and pharmacokinetics compared to two-dose ivermectin in a porcine …
C Bernigaud, F Fang, K Fischer, A Lespine… - PLoS neglected …, 2016 - journals.plos.org
Background Scabies is one of the commonest dermatological conditions globally; however it
is a largely underexplored and truly neglected infectious disease. Foremost, improvement in …
is a largely underexplored and truly neglected infectious disease. Foremost, improvement in …