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Potential role of IFN-α in COVID-19 patients and its underlying treatment options
Abstract The coronavirus disease (COVID-19) caused by a severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has spread rapidly worldwide. Given that this …
syndrome coronavirus 2 (SARS-CoV-2) has spread rapidly worldwide. Given that this …
Mutations in the genome of severe acute respiratory syndrome coronavirus 2: implications for COVID-19 severity and progression
AA Al-Qahtani - Journal of International Medical Research, 2022 - journals.sagepub.com
Coronaviridae is a large family of enveloped, positive-strand RNA viruses that has plagued
the world since it was discovered in humans in the 1960s. The recent severe acute …
the world since it was discovered in humans in the 1960s. The recent severe acute …
Genetic justification of COVID‐19 patient outcomes using DERGA, a novel data ensemble refinement greedy algorithm
Complement inhibition has shown promise in various disorders, including COVID‐19. A
prediction tool including complement genetic variants is vital. This study aims to identify …
prediction tool including complement genetic variants is vital. This study aims to identify …
SARS-CoV-2 and influenza A virus coinfections in ferrets
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and seasonal influenza
viruses are cocirculating in the human population. However, only a few cases of viral …
viruses are cocirculating in the human population. However, only a few cases of viral …
SARS-CoV-2 mutations and COVID-19 clinical outcome: mutation global frequency dynamics and structural modulation hold the key
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has had an enormous
burden on the healthcare system worldwide as a consequence of its new emerging variants …
burden on the healthcare system worldwide as a consequence of its new emerging variants …
Predicting COVID-19 disease severity from SARS-CoV-2 spike protein sequence by mixed effects machine learning
Epidemiological studies show that COVID-19 variants-of-concern, like Delta and Omicron,
pose different risks for severe disease, but they typically lack sequence-level information for …
pose different risks for severe disease, but they typically lack sequence-level information for …
Association between prognostic factors and the outcomes of patients infected with SARS-CoV-2 harboring multiple spike protein mutations
The outcome of SARS-CoV-2 infection is determined by multiple factors, including the viral,
host genetics, age, and comorbidities. This study investigated the association between …
host genetics, age, and comorbidities. This study investigated the association between …
[HTML][HTML] Interpretable and predictive deep neural network modeling of the SARS-Cov-2 spike protein sequence to predict COVID-19 disease severity
Simple Summary As COVID-19 shifts from pandemic to endemic, emerging variants may be
more or less virulent. Predicting whether an emerging COVID-19 variant has of high risk of …
more or less virulent. Predicting whether an emerging COVID-19 variant has of high risk of …
Severity of infection with the SARS-CoV-2 B. 1.1. 7 lineage among hospitalized COVID-19 patients in Belgium
N Van Goethem, M Vandromme, H Van Oyen… - PLoS …, 2022 - journals.plos.org
Introduction The pathogenesis of COVID-19 depends on the interplay between host
characteristics, viral characteristics and contextual factors. Here, we compare COVID-19 …
characteristics, viral characteristics and contextual factors. Here, we compare COVID-19 …
Structure and dynamics of whole-sequence homology model of ORF3a protein of SARS-CoV-2: An insight from microsecond molecular dynamics simulations
The ORF3a is a large accessory protein in severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), which plays an important role in virulence and viral replication; especially in …
(SARS-CoV-2), which plays an important role in virulence and viral replication; especially in …