[HTML][HTML] Angiotensin-converting enzyme 2 (ACE2): SARS-CoV-2 receptor and RAS modulator
J Bian, Z Li - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) outbreak is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). Angiotensin-converting enzyme 2 …
respiratory syndrome coronavirus 2 (SARS-CoV-2). Angiotensin-converting enzyme 2 …
Renal ischemia/reperfusion injury: An insight on in vitro and in vivo models
Optimal tissue oxygenation is essential for its normal function. Suboptimal oxygenation or
ischemia contributes to increased mortalities during various pathological conditions such as …
ischemia contributes to increased mortalities during various pathological conditions such as …
[HTML][HTML] To stress or not to stress: Brain-behavior-immune interaction may weaken or promote the immune response to SARS-CoV-2
The COVID-19 pandemic continues to strongly affect people with health disadvantages,
creating a heavy burden on medical systems and societies worldwide. Research is growing …
creating a heavy burden on medical systems and societies worldwide. Research is growing …
Outcomes associated with acute kidney disease: a systematic review and meta-analysis
Background Acute kidney disease (AKD) defines the period after kidney damage and it is a
critical period of both repair and fibrotic pathways. However, the outcomes of patients with …
critical period of both repair and fibrotic pathways. However, the outcomes of patients with …
Epigenetic and non-epigenetic regulation of Klotho in kidney disease
Klotho is a novel renoprotective anti-aging protein available in membrane-bound or soluble
form. Klotho is expressed in brain, pancreas, and other solid organs but shows highest …
form. Klotho is expressed in brain, pancreas, and other solid organs but shows highest …
Edema formation in congestive heart failure and the underlying mechanisms
Congestive heart failure (HF) is a complex disease state characterized by impaired
ventricular function and insufficient peripheral blood supply. The resultant reduced blood …
ventricular function and insufficient peripheral blood supply. The resultant reduced blood …
The Yin and Yang of ACE/ACE2 pathways: the rationale for the use of renin-angiotensin system inhibitors in COVID-19 patients
L Zamai - Cells, 2020 - mdpi.com
The article describes the rationale for inhibition of the renin-angiotensin system (RAS)
pathways as specific targets in patients infected by SARS-CoV-2 in order to prevent positive …
pathways as specific targets in patients infected by SARS-CoV-2 in order to prevent positive …
The influence of PM2.5 exposure on kidney diseases
W Xu, S Wang, L Jiang, X Sun… - Human & …, 2022 - journals.sagepub.com
The harm of air pollution to public health has become a research hotspot, especially
atmospheric fine-particulate matter (PM2. 5). In recent years, epidemiological investigations …
atmospheric fine-particulate matter (PM2. 5). In recent years, epidemiological investigations …
Altered kidney distribution and loss of ACE2 into the urine in acute kidney injury
There are diverse pathophysiological mechanisms involved in acute kidney injury (AKI).
Among them, overactivity of the renin-angiotensin system (RAS) has been described …
Among them, overactivity of the renin-angiotensin system (RAS) has been described …
[HTML][HTML] Klotho restoration via ACE2 activation: A potential therapeutic strategy against acute kidney injury-diabetes comorbidity
Acute kidney injury (AKI) is a collection of clinical syndromes with persistent increases in
morbidity and mortality rates. Hyperglycemia is a risk factor for AKI development. Renin …
morbidity and mortality rates. Hyperglycemia is a risk factor for AKI development. Renin …