Advanced drug delivery to the lymphatic system: lipid-based nanoformulations

AA Khan, J Mudassir, N Mohtar… - International journal of …, 2013 - Taylor & Francis
The delivery of drugs and bioactive compounds via the lymphatic system is complex and
dependent on the physiological uniqueness of the system. The lymphatic route plays an …

[HTML][HTML] Understanding peroral absorption: regulatory aspects and contemporary approaches to tackling solubility and permeability hurdles

PB Shekhawat, VB Pokharkar - Acta pharmaceutica sinica B, 2017 - Elsevier
Oral drug absorption is a process influenced by the physicochemical and biopharmaceutical
properties of the drug and its inter-relationship with the gastrointestinal tract. Drug solubility …

Characterization and Applications in Drug Delivery

SA Chime, FC Kenechukwu… - … of nanotechnology in drug …, 2014 - books.google.com
An ideal drug delivery system fulfils the objective of maximizing therapeutic effect while
minimizing toxicity. With the progress in time and advances in science and technology …

From nanoemulsions to self-nanoemulsions, with recent advances in self-nanoemulsifying drug delivery systems (SNEDDS)

FU Rehman, KU Shah, SU Shah, IU Khan… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: Lipid-based drug delivery systems (LBDDS) are the most promising technique
to formulate the poorly water soluble drugs. Nanotechnology strongly influences the …

Self-nanoemulsifying drug delivery system (SNEDDS) with enhanced solubilization of nystatin for treatment of oral candidiasis: Design, optimization, in vitro and in …

AA Kassem, AM Mohsen, RS Ahmed… - Journal of molecular …, 2016 - Elsevier
The aim of the present study is to develop and optimize self-nanoemulsifying drug delivery
systems (SNEDDSs) to improve the per-oral bioavailability of poorly soluble polyene …

[HTML][HTML] Formulation development, optimization by Box-Behnken design, characterization, in vitro, ex-vivo, and in vivo evaluation of bosentan-loaded self …

DY Usta, B Timur, ZS Teksin - European Journal of Pharmaceutical …, 2022 - Elsevier
This study aimed to develop and optimize a self-nanoemulsifying drug delivery system
(SNEDDS) of bosentan (BOS) to solve its poor oral bioavailability due to low water solubility …

Development of docetaxel-loaded solid self-nanoemulsifying drug delivery system (SNEDDS) for enhanced chemotherapeutic effect

YG Seo, DH Kim, T Ramasamy, JH Kim… - International journal of …, 2013 - Elsevier
The main purpose of this study was to investigate the potential of self-nano-emulsifying drug
delivery system (SNEDDS) in improving the bioavailability of docetaxel (DCT) and its …

Box–Behnken designs and their applications in pharmaceutical product development

S Beg, S Akhter - Design of experiments for pharmaceutical product …, 2021 - Springer
Abstract Box–Behnken designs (BBDs) are the very efficient response surface design which
provides information exclusively on the effect of experiment variables and overall …

Reprint of: Nanocarrier systems for oral drug delivery: Do we really need them?

A Bernkop-Schnürch - European Journal of Pharmaceutical Sciences, 2013 - Elsevier
In particular since the last two decades there is constantly increasing interest in nanocarrier
systems. They are utilized in order to overcome the major challenges being associated with …

Curcumin loaded ethosomes for transdermal application: Formulation, optimization, in-vitro and in-vivo study

IB Pathan, BP Jaware, S Shelke, W Ambekar - Journal of Drug Delivery …, 2018 - Elsevier
Curcumin has an excellent safety profile with varied pleiotropic actions, including anti-
inflammatory, antioxidant, antitumoural, anticancer, and antimicrobial activities, with the …