Since the first pioneering studies on small deuterated peptides dating more than 20 years
ago, 1H detection has evolved into the most efficient approach for investigation of …

Solid-state nuclear magnetic resonance (ssNMR) is indispensable for studying the
structures, dynamics, and interactions of insoluble proteins in native or native-like …

Solid-state nuclear magnetic resonance (NMR) is a potent tool for studying the structures
and dynamics of insoluble proteins. It starts with signal assignment through multi …

Chromatin phase separation is dynamically regulated by many factors, such as post-
translational modifications and effector proteins, and plays a critical role in genomic …

Aggregation intermediates play a pivotal role in the assembly of amyloid fibrils, which are
central to the pathogenesis of neurodegenerative diseases. The structures of filamentous …

Additional phase modulation (APM) is proposed to generally enhance the theoretical
efficiency of homonuclear double‐quantum (DQ) recoupling in solid‐state NMR. APM …

Carbon–carbon dipolar recoupling sequences are frequently used building blocks in routine
magic-angle spinning NMR experiments. While broadband homonuclear first-order dipolar …

Understanding macromolecular function, interactions, and stability hinges on detailed
assessment of conformational ensembles. For solid proteins, accurate elucidation of the …

Abstract 1H-detected solid-state NMR spectroscopy has been becoming increasingly
popular for the characterization of protein structure, dynamics, and function. Recently, we …

The long-range heteronuclear correlation remains a significant challenge in solid-state
nuclear magnetic resonance (NMR), which is critical in the structural elucidation of …