Biological and functional multimorbidity—from mechanisms to management
Globally, the number of people with multiple co-occurring diseases will increase
substantially over the coming decades, with important consequences for patients, carers …
substantially over the coming decades, with important consequences for patients, carers …
Map** and evaluating national data flows: transparency, privacy, and guiding infrastructural transformation
The importance of big health data is recognised worldwide. Most UK National Health
Service (NHS) care interactions are recorded in electronic health records, resulting in an …
Service (NHS) care interactions are recorded in electronic health records, resulting in an …
Association of COVID-19 with major arterial and venous thrombotic diseases: a population-wide cohort study of 48 million adults in England and Wales
Background: Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
induces a prothrombotic state, but long-term effects of COVID-19 on incidence of vascular …
induces a prothrombotic state, but long-term effects of COVID-19 on incidence of vascular …
The impact of the COVID-19 pandemic on cardiovascular disease prevention and management
Abstract How the Coronavirus Disease 2019 (COVID-19) pandemic has affected prevention
and management of cardiovascular disease (CVD) is not fully understood. In this study, we …
and management of cardiovascular disease (CVD) is not fully understood. In this study, we …
Changes in COVID-19-related mortality across key demographic and clinical subgroups in England from 2020 to 2022: a retrospective cohort study using the …
Background COVID-19 has been shown to differently affect various demographic and
clinical population subgroups. We aimed to describe trends in absolute and relative COVID …
clinical population subgroups. We aimed to describe trends in absolute and relative COVID …
Cohort study of cardiovascular safety of different COVID-19 vaccination doses among 46 million adults in England
The first dose of COVID-19 vaccines led to an overall reduction in cardiovascular events,
and in rare cases, cardiovascular complications. There is less information about the effect of …
and in rare cases, cardiovascular complications. There is less information about the effect of …
Profiling post-COVID-19 condition across different variants of SARS-CoV-2: a prospective longitudinal study in unvaccinated wild-type, unvaccinated alpha-variant …
Background Self-reported symptom studies rapidly increased understanding of SARS-CoV-
2 during the COVID-19 pandemic and enabled monitoring of long-term effects of COVID-19 …
2 during the COVID-19 pandemic and enabled monitoring of long-term effects of COVID-19 …
Transforming and evaluating the UK Biobank to the OMOP Common Data Model for COVID-19 research and beyond
Objective The coronavirus disease 2019 (COVID-19) pandemic has demonstrated the value
of real-world data for public health research. International federated analyses are crucial for …
of real-world data for public health research. International federated analyses are crucial for …
Complex patterns of multimorbidity associated with severe COVID-19 and long COVID
Background Early evidence that patients with (multiple) pre-existing diseases are at highest
risk for severe COVID-19 has been instrumental in the pandemic to allocate critical care …
risk for severe COVID-19 has been instrumental in the pandemic to allocate critical care …
Profiling post-COVID syndrome across different variants of SARS-CoV-2
Background Self-reported symptom studies rapidly increased our understanding of SARS-
CoV-2 during the pandemic and enabled the monitoring of long-term effects of COVID-19 …
CoV-2 during the pandemic and enabled the monitoring of long-term effects of COVID-19 …