In humans, cell fusion is restricted to only a few cell types under normal conditions. In the
placenta, cell fusion is a critical process for generating syncytiotrophoblast: the giant …

Preeclampsia remains a leading cause of maternal and fetal mortality, due to ineffective
treatment and diagnostic strategies, compounded by the lack of clarity on the etiology of the …

The placenta is one of the organs with the highest evolutionary diversity among animal
species. In consequence, an animal model that reflects human placentation exactly does not …

BACKGROUND The establishment of maternal–fetal crosstalk is vital to a successful
pregnancy. Glycosylation is a post-translational modification in which glycans …

Although the precise pathophysiology of pre-eclampsia remains unknown, this condition
continues to be a major cause of maternal and fetal mortality. Early prediction of pre …

Galectins are a large family of carbohydrate binding proteins with members in nearly every
lineage of multicellular life. Through tandem and en-mass genome duplications, over 15 …

Galectins are glycan-binding proteins that regulate innate and adaptive immune responses,
and some confer maternal-fetal immune tolerance in eutherian mammals. A chromosome 19 …

Problem The T-cell immunoglobulin and mucin domain (TIM) family is a relatively newly
described group of molecules with a conserved structure and important immunological …

Galectins are a phylogenetically conserved family of soluble β-galactoside binding proteins,
consisting of 15 different types, each with a specific function. Galectins contribute to …

Exposure to particulate air pollution and socioeconomic risk factors are shown to be
independently associated with adverse pregnancy outcomes; however, their confounding …