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Recent advances in nanomaterial-based synergistic combination cancer immunotherapy
In recent years, conventional treatments including surgery, chemotherapy and radiotherapy
have been the main approaches in tumour therapy. Cancer immunotherapy is a new …
have been the main approaches in tumour therapy. Cancer immunotherapy is a new …
Triggers for the onset and recurrence of psoriasis: a review and update
S Liu, M He, J Jiang, X Duan, B Chai, J Zhang… - Cell Communication and …, 2024 - Springer
Psoriasis is an immune-mediated inflammatory skin disease, involving a complex interplay
between genetic and environmental factors. Previous studies have demonstrated that …
between genetic and environmental factors. Previous studies have demonstrated that …
[HTML][HTML] Phosphoinositide 3-kinase regulates glycolysis through mobilization of aldolase from the actin cytoskeleton
Summary The phosphoinositide 3-kinase (PI3K) pathway regulates multiple steps in glucose
metabolism and also cytoskeletal functions, such as cell movement and attachment. Here …
metabolism and also cytoskeletal functions, such as cell movement and attachment. Here …
RAS interaction with PI3K: more than just another effector pathway
RAS proteins are small GTPases known for their involvement in oncogenesis: around 25%
of human tumors present mutations in a member of this family. RAS operates in a complex …
of human tumors present mutations in a member of this family. RAS operates in a complex …
Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis
A Dunaif - Endocrine reviews, 1997 - academic.oup.com
Insulin Resistance and the Polycystic Ovary Syndrome: Mechanism and Implications for
Pathogenesis* | Endocrine Reviews | Oxford Academic Skip to Main Content Advertisement …
Pathogenesis* | Endocrine Reviews | Oxford Academic Skip to Main Content Advertisement …
RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs
The immunosuppressants rapamycin and FK506 bind to the same intracellular protein, the
immunophilin FKBP12. The FKBP12-FK506 complex interacts with and inhibits the Ca*+ …
immunophilin FKBP12. The FKBP12-FK506 complex interacts with and inhibits the Ca*+ …
Epidermal growth factor-related peptides and their receptors in human malignancies
The development of cancer is due to the accumulation of multiple somatic mutations and in
some cases due to germline mutations, which occur in malignancies such as retinoblastoma …
some cases due to germline mutations, which occur in malignancies such as retinoblastoma …
The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases
X-linked agammaglobulinaemia (XLA) is a human immunodeficiency caused by failure of
pre-B cells in the bone marrow to develop into circulating mature B cells. A novel gene has …
pre-B cells in the bone marrow to develop into circulating mature B cells. A novel gene has …
KiSS-1, a novel human malignant melanoma metastasis-suppressor gene
JH Lee, ME Miele, DJ Hicks, KK Phillips… - JNCI: Journal of the …, 1996 - academic.oup.com
Background Microcell-mediated transfer of chromosome 6 into human C8161 and MelJuSo
melanoma cells suppresses their ability to metastasize by at least 95% without affecting their …
melanoma cells suppresses their ability to metastasize by at least 95% without affecting their …
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
The most recently discovered PTEN tumor suppressor gene has been found to be defective
in a large number of human cancers. In addition, germ-line mutations in PTEN result in the …
in a large number of human cancers. In addition, germ-line mutations in PTEN result in the …