The hippocampus is a part of the brain's medial temporal lobe that is located under the
cortex. It belongs to the limbic system and helps to collect and transfer information from short …

Chronic neuropathic pain and comorbid depression syndrome (CDS) is a major worldwide
health problem that affects the quality of life of patients and imposes a tremendous …

Anxiety and depression are frequently observed in patients suffering from trigeminal
neuralgia (TN), but neural circuits and mechanisms underlying this association are poorly …

Introduction The antidepressant properties of Hypericum species are known. Hyperibone J,
a principal component found in the flowers of Hypericum bellum, exhibited in vitro anti …

Glial activation and dysregulation of adenosine triphosphate (ATP)/adenosine are involved
in the neuropathology of several neuropsychiatric illnesses. The ventral hippocampus …

Introduction This study aimed to identify the effect of electroacupuncture (EA) treatment on
post-stroke depression (PSD) and explore whether cannabinoid receptor 1 (CB1R) …

The role of astrocytes in modulating synaptic plasticity is an important question that until
recently was not addressed due to limitations of previously existing technology. In the …

The elaborate mechanisms of depression have always been a research hotspot in recent
years, and the pace of research has never ceased. The P2X7 receptor (P2X7R) belongs to …

Neuropathic pain (NP) is known to be associated with abnormal changes in specific brain
regions, but the complex neural network behind it is vast and complex and lacks a …

Objective This review aims to systematically summarize the methods of establishing various
models of trigeminal neuralgia (TN), the scope of application, and current animals used in …