Exosomes participate in many physiological and pathological processes by regulating cell–
cell communication, which are involved in numerous diseases, including osteoarthritis (OA) …

Extracellular vesicles (EVs) are released from all cells in the body, forming an important
intercellular communication network that contributes to health and disease. The contents of …

Rationale: Aberrant activation of macrophages with mitochondria dismiss was proved to be
associated with pathogenesis of ALI (acute lung injury). Exosomes from adipose-derived …

Cellular senescence is a persistently hypoproliferative state with diverse stressors in a
specific aging microenvironment. Senescent cells have a double‐edged sword effect: they …

Degenerative disorders of joints, especially osteoarthritis (OA), result in persistent pain and
disability and high costs to society. Nevertheless, the molecular mechanisms of OA have not …

It is clear from Part I of this series that extracellular vesicles (EVs) play a critical role in
maintaining the homeostasis of most, if not all, normal physiological systems. However, the …

Osteoarthritis (OA) is a highly prevalent whole-joint disease that causes disability and pain
and affects a patient's quality of life. However, currently, there is a lack of effective early …

Osteoarthritis (OA) is a prevalent chronic whole-joint disease characterized by low-grade
systemic inflammation, degeneration of joint-related tissues such as articular cartilage, and …

Osteoarthritis (OA) is a prevalent degenerative joint disease characterized by cartilage loss
and accounts for a major source of pain and disability worldwide. However, effective …

Abstract Metal-organic frameworks (MOFs), a class of hybrid materials, consist of organic
linkers and bridging metal ions or clusters. Their tunable pore sizes, large surface area …