Sex hormones in acquired immunity and autoimmune disease
VR Moulton - Frontiers in immunology, 2018 - frontiersin.org
Women have stronger immune responses to infections and vaccination than men.
Paradoxically, the stronger immune response comes at a steep price, which is the high …
Paradoxically, the stronger immune response comes at a steep price, which is the high …
Estrogen receptor signaling in the immune system
The immune system functions in a sexually dimorphic manner, with females exhibiting more
robust immune responses than males. However, how female sex hormones affect immune …
robust immune responses than males. However, how female sex hormones affect immune …
Cellular and molecular pathways of COVID-19 and potential points of therapeutic intervention
JP Hussman - Frontiers in pharmacology, 2020 - frontiersin.org
With the objective of linking early findings relating to the novel SARS-CoV-2 coronavirus
with potentially informative findings from prior research literature and to promote …
with potentially informative findings from prior research literature and to promote …
Autoimmune disease in women: endocrine transition and risk across the lifespan
MK Desai, RD Brinton - Frontiers in endocrinology, 2019 - frontiersin.org
Women have a higher incidence and prevalence of autoimmune diseases than men, and
85% or more patients of multiple autoimmune diseases are female. Women undergo …
85% or more patients of multiple autoimmune diseases are female. Women undergo …
The roles of sex hormones in the course of atopic dermatitis
N Kanda, T Hoashi, H Saeki - International journal of molecular sciences, 2019 - mdpi.com
Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by T helper 2 cell
(Th2)-shifted abnormal immunity, skin barrier impairment, and pruritus. The prevalence of …
(Th2)-shifted abnormal immunity, skin barrier impairment, and pruritus. The prevalence of …
[HTML][HTML] Therapeutic opportunities in cancer therapy: targeting the p53-MDM2/MDMX interactions
Ubiquitination is a key enzymatic post-translational modification that influences p53 stability
and function. p53 protein regulates the expression of MDM2 (mouse double-minute 2 …
and function. p53 protein regulates the expression of MDM2 (mouse double-minute 2 …
[HTML][HTML] Sex-tailored pharmacology and COVID-19: Next steps towards appropriateness and health equity
Making gender bias visible allows to fill the gaps in knowledge and understand health
records and risks of women and men. The coronavirus disease 2019 (COVID-19) pandemic …
records and risks of women and men. The coronavirus disease 2019 (COVID-19) pandemic …
Estrogen acts through estrogen receptor-β to promote mannan-induced psoriasis-like skin inflammation
H Wu, L Zeng, J Ou, T Wang, Y Chen… - Frontiers in …, 2022 - frontiersin.org
Sex-bias is more obvious in several autoimmune disorders, but not in psoriasis. However,
estrogen levels fluctuate during puberty, menstrual cycle, pregnancy, and menopause …
estrogen levels fluctuate during puberty, menstrual cycle, pregnancy, and menopause …
Estrogen deprivation and estrogen receptor α antagonism decrease DSS colitis in female mice
A Hjelt, S Anttila, A Wiklund, A Rokka… - Pharmacology …, 2024 - Wiley Online Library
The association of hormonal contraception with increased risk of inflammatory bowel
disease (IBD) observed in females suggests involvement of ovarian hormones, such as …
disease (IBD) observed in females suggests involvement of ovarian hormones, such as …
Selective estrogen receptor modulators in COVID-19: a possible therapeutic option?
A Calderone, F Menichetti, F Santini… - Frontiers in …, 2020 - frontiersin.org
Male and female genders exhibit significant differences in the outcome of infective diseases
caused by several viral pathogens. Along with behavioral or social factors which can affect …
caused by several viral pathogens. Along with behavioral or social factors which can affect …