Expanding the diversity of origin of transfer-containing sequences in mobilizable plasmids

M Ares-Arroyo, A Nucci, EPC Rocha - Nature Microbiology, 2024 - nature.com
Conjugative plasmids are important drivers of bacterial evolution. Most plasmids lack genes
for conjugation and characterized origins of transfer (oriT), which has hampered our …

Deciphering the relative importance of genetic elements in hypervirulent Klebsiella pneumoniae to guide countermeasure development

TA Russo, U Carlino-MacDonald, ZJ Drayer… - …, 2024 - thelancet.com
Background Quantitating the contribution of phenotype-responsible elements in
hypervirulent Klebsiella pneumoniae is needed. Methods Isogenic mutants of four …

A genome-wide One Health study of Klebsiella pneumoniae in Norway reveals overlap** populations but few recent transmission events across reservoirs

MAK Hetland, MA Winkler, H Kaspersen… - bioRxiv, 2024 - biorxiv.org
Members of the Klebsiella pneumoniae species complex (KpSC) are opportunistic
pathogens that cause severe and difficult-to-treat infections. KpSC are common in non …

Identification of novel origins of transfer across bacterial plasmids

M Ares-Arroyo, A Nucci, EPC Rocha - bioRxiv, 2024 - biorxiv.org
Conjugative plasmids are important drivers of bacterial evolution, but most plasmids lack
genes for conjugation. It is currently not known if the latter can transfer because origins of …