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Plasmacytoid dendritic cells: development, regulation, and function
B Reizis - Immunity, 2019 - cell.com
Plasmacytoid dendritic cells (pDCs) are a unique sentinel cell type that can detect pathogen-
derived nucleic acids and respond with rapid and massive production of type I interferon …
derived nucleic acids and respond with rapid and massive production of type I interferon …
Genetic models of human and mouse dendritic cell development and function
Dendritic cells (DCs) develop in the bone marrow from haematopoietic progenitors that have
numerous shared characteristics between mice and humans. Human counterparts of mouse …
numerous shared characteristics between mice and humans. Human counterparts of mouse …
Single-cell RNA-seq reveals cell type–specific molecular and genetic associations to lupus
Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease. Knowledge
of circulating immune cell types and states associated with SLE remains incomplete. We …
of circulating immune cell types and states associated with SLE remains incomplete. We …
The multifaceted biology of plasmacytoid dendritic cells
Plasmacytoid dendritic cells (pDCs) are a unique DC subset that specializes in the
production of type I interferons (IFNs). pDCs promote antiviral immune responses and have …
production of type I interferons (IFNs). pDCs promote antiviral immune responses and have …
Distinct progenitor lineages contribute to the heterogeneity of plasmacytoid dendritic cells
Plasmacytoid dendritic cells (pDCs) are an immune subset devoted to the production of high
amounts of type 1 interferons in response to viral infections. Whereas conventional dendritic …
amounts of type 1 interferons in response to viral infections. Whereas conventional dendritic …
Plasmacytoid dendritic cells develop from Ly6D+ lymphoid progenitors distinct from the myeloid lineage
Dendritic cells (DC) are currently classified as conventional DCs (cDCs) and plasmacytoid
DCs (pDCs). Through a combination of single-cell transcriptomic analysis, mass cytometry …
DCs (pDCs). Through a combination of single-cell transcriptomic analysis, mass cytometry …
Dandelion uses the single-cell adaptive immune receptor repertoire to explore lymphocyte developmental origins
Assessment of single-cell gene expression (single-cell RNA sequencing) and adaptive
immune receptor (AIR) sequencing (scVDJ-seq) has been invaluable in studying …
immune receptor (AIR) sequencing (scVDJ-seq) has been invaluable in studying …
The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting
Dendritic cells (DCs) form a remarkable cellular network that shapes adaptive immune
responses according to peripheral cues. After four decades of research, we now know that …
responses according to peripheral cues. After four decades of research, we now know that …
Development of monocytes, macrophages, and dendritic cells
Monocytes and macrophages are critical effectors and regulators of inflammation and the
innate immune response, the immediate arm of the immune system. Dendritic cells initiate …
innate immune response, the immediate arm of the immune system. Dendritic cells initiate …
Immunosuppressive strategies that are mediated by tumor cells
Despite major advances in understanding the mechanisms leading to tumor immunity, a
number of obstacles hinder the successful translation of mechanistic insights into effective …
number of obstacles hinder the successful translation of mechanistic insights into effective …