Hydrazinated geraniol derivatives as potential broad‐spectrum antiprotozoal agents

J Jooste, LJ Legoabe, K Ilbeigi, G Caljon… - Archiv der …, 2024 - Wiley Online Library
Geraniol, a primary component of several essential oils, has been associated with broad‐
spectrum antiprotozoal activities, although moderate to weak. This study primarily …

Nanomolar activity of coumarin-3-thiosemicarbazones targeting Trypanosoma cruzi cruzain and the T. brucei cathepsin L-like protease

JA Nunes, PF da Silva Santos-Júnior… - European Journal of …, 2025 - Elsevier
Trypanosoma cruzi (T. cruzi) and Trypanosoma brucei (T. brucei) urgently demand
innovative drug development due to their impact on public health worldwide. Their cysteine …