Human dendritic cells: their heterogeneity and clinical application potential in cancer immunotherapy
Dendritic cells (DC) are professional antigen presenting cells, uniquely able to induce naïve
T cell activation and effector differentiation. They are, likewise, involved in the induction and …
T cell activation and effector differentiation. They are, likewise, involved in the induction and …
Dendritic cell subsets and locations
S Balan, M Saxena, N Bhardwaj - International review of cell and molecular …, 2019 - Elsevier
Dendritic cells (DCs) are a unique class of immune cells that act as a bridge between innate
and adaptive immunity. The discovery of DCs by Cohen and Steinman in 1973 laid the …
and adaptive immunity. The discovery of DCs by Cohen and Steinman in 1973 laid the …
[HTML][HTML] Transcriptional and functional analysis of CD1c+ human dendritic cells identifies a CD163+ subset priming CD8+ CD103+ T cells
P Bourdely, G Anselmi, K Vaivode, RN Ramos… - Immunity, 2020 - cell.com
Dendritic cells (DCs) are antigen-presenting cells controlling T cell activation. In humans, the
diversity, ontogeny, and functional capabilities of DC subsets are not fully understood. Here …
diversity, ontogeny, and functional capabilities of DC subsets are not fully understood. Here …
Dexosomes as a cell-free vaccine for cancer immunotherapy
Dendritic cells (DCs) secrete vast quantities of exosomes termed as dexosomes.
Dexosomes are symmetric nanoscale heat-stable vesicles that consist of a lipid bilayer …
Dexosomes are symmetric nanoscale heat-stable vesicles that consist of a lipid bilayer …
Osteoimmunomodulatory effects of biomaterial modification strategies on macrophage polarization and bone regeneration
Y **e, C Hu, Y Feng, D Li, T Ai, Y Huang… - Regenerative …, 2020 - academic.oup.com
Biomaterials as bone substitutes are always considered as foreign bodies that can trigger
host immune responses. Traditional designing principles have been always aimed at …
host immune responses. Traditional designing principles have been always aimed at …
The role of type-2 conventional dendritic cells in the regulation of tumor immunity
Y Saito, S Komori, T Kotani, Y Murata, T Matozaki - Cancers, 2022 - mdpi.com
Simple Summary Recent studies revealed that type-2 conventional dendritic cells (cDC2s)
play an important role in antitumor immunity by promoting cytotoxic T-cell responses and …
play an important role in antitumor immunity by promoting cytotoxic T-cell responses and …
Dendritic cells in the tumor microenvironment: prognostic and theranostic impact
J Verneau, C Sautés-Fridman, CM Sun - Seminars in immunology, 2020 - Elsevier
Among all immune cells, dendritic cells (DC) are the most potent APCs in the immune
system and are central players of the adaptive immune response. There are phenotypically …
system and are central players of the adaptive immune response. There are phenotypically …
[HTML][HTML] Dendritic cells and CCR7 expression: an important factor for autoimmune diseases, chronic inflammation, and cancer
EP Brandum, AS Jørgensen, MM Rosenkilde… - International journal of …, 2021 - mdpi.com
Chemotactic cytokines—chemokines—control immune cell migration in the process of
initiation and resolution of inflammatory conditions as part of the body's defense system …
initiation and resolution of inflammatory conditions as part of the body's defense system …
The role of dendritic cells in cancer
YS Lee, KJ Radford - International review of cell and molecular biology, 2019 - Elsevier
Cancer immunotherapy harnesses the ability of the immune system to recognize and
eliminate cancer. The potent ability of dendritic cells (DCs) to initiate and regulate adaptive …
eliminate cancer. The potent ability of dendritic cells (DCs) to initiate and regulate adaptive …
Immune cellular components and signaling pathways in the tumor microenvironment
During the past decade there has been a revolution in cancer therapeutics by the
emergence of antibody-based and cell-based immunotherapies that modulate immune …
emergence of antibody-based and cell-based immunotherapies that modulate immune …