During division, eukaryotic cells undergo a dramatic, complex and coordinated remodelling
of their cytoskeleton and membranes. For cell division to occur, chromosomes must be …

Rab molecular switches are key players in defining membrane identity and regulating
intracellular trafficking events in eukaryotic cells. In spite of their global structural similarity …

Cell division ends with the physical separation of the two daughter cells, a process known as
cytokinesis. This final event ensures that nuclear and cytoplasmic contents are accurately …

Actin is the most abundant protein in almost all the eukaryotic cells. Actin amino acid
sequences are highly conserved and have not changed a lot during the progress of …

Cells don't simply separate at cytokinesis. While furrow contraction critically relies on myosin-
II and F-actin, post-furrowing steps are less understood but involve the constriction of …

Golgi phosphoprotein 3 (GOLPH3), a Phosphatidylinositol 4-Phosphate [PI (4) P] effector at
the Golgi, is required for Golgi ribbon structure maintenance, vesicle trafficking and Golgi …

GOLPH3 is a peripheral membrane protein localized to the Golgi and its vesicles, but its
purpose had been unclear. We found that GOLPH3 binds specifically to the …

Phosphatidylinositol is the parent lipid for the synthesis of seven phosphorylated inositol
lipids and each of them play specific roles in numerous processes including receptor …

Phosphoinositides are low abundant but essential phospholipids in eukaryotic cells and
refer to phosphatidylinositol and its seven polyphospho-derivatives. In this review, we …

Glycosylation is the most common post-translational modification of proteins; it mediates
their correct folding and stability, as well as their transport through the secretory transport …