The red edge: bilin-binding photoreceptors as optogenetic tools and fluorescence reporters

K Tang, HM Beyer, MD Zurbriggen… - Chemical …, 2021 - ACS Publications
This review adds the bilin-binding phytochromes to the Chemical Reviews thematic issue
“Optogenetics and Photopharmacology”. The work is structured into two parts. We first …

Cyanobacteriochromes: A rainbow of photoreceptors

NC Rockwell, JC Lagarias - Annual review of microbiology, 2024 - annualreviews.org
Widespread phytochrome photoreceptors use photoisomerization of linear tetrapyrrole
(bilin) chromophores to measure the ratio of red to far-red light. Cyanobacteria also contain …

Green/red light-sensing mechanism in the chromatic acclimation photosensor

T Nagae, Y Fujita, T Tsuchida, T Kamo, R Seto… - Science …, 2024 - science.org
Certain cyanobacteria alter their photosynthetic light absorption between green and red, a
phenomenon called complementary chromatic acclimation. The acclimation is regulated by …

[HTML][HTML] Cyanobacteriochromes from Gloeobacterales provide new insight into the diversification of cyanobacterial photoreceptors

NC Rockwell, JC Lagarias - Journal of molecular biology, 2024 - Elsevier
The phytochrome superfamily comprises three groups of photoreceptors sharing a
conserved GAF (cGMP-specific phosphodiesterases, cyanobacterial adenylate cyclases …

Probing Bilin–Protein Interaction in the Protochromic Photocycle of Cyanobacteriochrome RcaE by Site-Directed Mutagenesis

T Kamo, T Matsushita, M Hamada… - Plant And Cell …, 2024 - academic.oup.com
Cyanobacteriochromes (CBCRs) are members of the phytochrome superfamily of
photosensor proteins that bind a bilin chromophore. CBCRs exhibit substantial diversity in …

[HTML][HTML] Detailed insight into the ultrafast photoconversion of the cyanobacteriochrome Slr1393 from Synechocystis sp.

C Slavov, X Xu, K Zhao, W Gaertner… - Biochimica et Biophysica …, 2015 - Elsevier
The initial light-induced processes of the photochromic, phycocyanobilin-binding GAF
domain of Slr1393 from Synechocystis sp. PCC6803 have been studied by ultrafast transient …

The interplay between chromophore and protein determines the extended excited state dynamics in a single-domain phytochrome

C Slavov, T Fischer, A Barnoy, H Shin, AG Rao… - Proceedings of the …, 2020 - pnas.org
Phytochromes are a diverse family of bilin-binding photoreceptors that regulate a wide
range of physiological processes. Their photochemical properties make them attractive for …

Structural basis of the protochromic green/red photocycle of the chromatic acclimation sensor RcaE

T Nagae, M Unno, T Koizumi, Y Miyanoiri… - Proceedings of the …, 2021 - pnas.org
Cyanobacteriochromes (CBCRs) are bilin-binding photosensors of the phytochrome
superfamily that show remarkable spectral diversity. The green/red CBCR subfamily is …

Identification of the deprotonated pyrrole nitrogen of the bilin-based photoreceptor by Raman spectroscopy with an advanced computational analysis

S Osoegawa, R Miyoshi, K Watanabe… - The Journal of …, 2019 - ACS Publications
Phytochrome and cyanobacteriochrome utilize a linear methine-bridged tetrapyrrole (bilin)
to control numerous biological processes. They show a reversible photoconversion between …

Protochromic absorption changes in the two-cysteine photocycle of a blue/orange cyanobacteriochrome

T Sato, T Kikukawa, R Miyoshi, K Kajimoto… - Journal of Biological …, 2019 - jbc.org
Cyanobacteriochromes (CBCRs) are phytochrome-related photosensors with diverse
spectral sensitivities spanning the entire visible spectrum. They covalently bind bilin …