Remodeling of membrane shape and topology by curvature elasticity and membrane tension

R Lipowsky - Advanced Biology, 2022 - Wiley Online Library
Cellular membranes exhibit a fascinating variety of different morphologies, which are
continuously remodeled by transformations of membrane shape and topology. This …

Biomolecular condensates mediate bending and scission of endosome membranes

Y Wang, S Li, M Mokbel, AI May, Z Liang, Y Zeng… - Nature, 2024 - nature.com
Multivesicular bodies are key endosomal compartments implicated in cellular quality control
through their degradation of membrane-bound cargo proteins,–. The ATP-consuming …

Piezo's membrane footprint and its contribution to mechanosensitivity

CA Haselwandter, R MacKinnon - Elife, 2018 - elifesciences.org
Piezo1 is an ion channel that gates open when mechanical force is applied to a cell
membrane, thus allowing cells to detect and respond to mechanical stimulation. Molecular …

Quantitative prediction and measurement of Piezo's membrane footprint

CA Haselwandter, YR Guo, Z Fu… - Proceedings of the …, 2022 - pnas.org
Piezo proteins are mechanosensitive ion channels that can locally curve the membrane into
a dome shape [YR Guo, R. MacKinnon, eLife 6, e33660 (2017)]. The curved shape of the …

Budding and fission of nanovesicles induced by membrane adsorption of small solutes

R Ghosh, V Satarifard, A Grafmüller, R Lipowsky - ACS nano, 2021 - ACS Publications
Membrane budding and fission are essential cellular processes that produce new
membrane compartments during cell and organelle division, for intracellular vesicle …

Dynamic shapes of floppy vesicles enclosing active Brownian particles with membrane adhesion

P Iyer, G Gompper, DA Fedosov - Soft matter, 2023 - pubs.rsc.org
Recent advances in micro-and nano-technologies allow the construction of complex active
systems from biological and synthetic materials. An interesting example is active vesicles …

Active shape oscillations of giant vesicles with cyclic closure and opening of membrane necks

S Christ, T Litschel, P Schwille, R Lipowsky - Soft Matter, 2021 - pubs.rsc.org
Reaction-diffusion systems encapsulated within giant unilamellar vesicles (GUVs) can lead
to shape oscillations of these vesicles as recently observed for the bacterial Min protein …

Understanding giant vesicles: A theoretical perspective

R Lipowsky - The giant vesicle book, 2019 - taylorfrancis.com
Giant vesicles respond to environmental changes by remodeling both their shape and their
local membrane composition. Particularly interesting morphological transitions are provided …

Role of shape in particle-lipid membrane interactions: from surfing to full engulfment

S Van der Ham, J Agudo-Canalejo, HR Vutukuri - ACS nano, 2024 - ACS Publications
Understanding and manipulating the interactions between foreign bodies and cell
membranes during endo-and phagocytosis is of paramount importance, not only for the fate …