[HTML][HTML] Human plasma metabolomics in age-related macular degeneration: meta-analysis of two cohorts

I Laíns, W Chung, RS Kelly, J Gil, M Marques, P Barreto… - Metabolites, 2019 - mdpi.com
The pathogenesis of age-related macular degeneration (AMD), a leading cause of blindness
worldwide, remains only partially understood. This has led to the current lack of accessible …

Metabolomic-derived endotypes of age-related macular degeneration (AMD): a step towards identification of disease subgroups

K Mendez, I Lains, RS Kelly, J Gil, R Silva, J Miller… - Scientific Reports, 2024 - nature.com
Age-related macular degeneration (AMD) is a leading cause of blindness worldwide, with a
complex pathophysiology and phenotypic diversity. Here, we apply Similarity Network …

Assessment of patient specific information in the wild on fundus photography and optical coherence tomography

MR Munk, T Kurmann, P Marquez-Neila… - Scientific reports, 2021 - nature.com
In this paper we analyse the performance of machine learning methods in predicting patient
information such as age or sex solely from retinal imaging modalities in a heterogeneous …

Light color efficiency-balanced trans-palpebral illumination for widefield fundus photography of the retina and choroid

T Son, J Ma, D Toslak, A Rossi, H Kim, RVP Chan… - Scientific Reports, 2022 - nature.com
A wide-field fundus camera, which can selectively evaluate the retina and choroid, is
desirable for better detection and treatment evaluation of eye diseases. Trans-palpebral …

Age-Related Macular Degeneration Staging by Color Fundus Photography vs. Multimodal Imaging—Epidemiological Implications (The Coimbra Eye Study—Report 6 …

C Farinha, ML Cachulo, R Coimbra, D Alves… - Journal of clinical …, 2020 - mdpi.com
Epidemiology of age-related macular degeneration (AMD) is based on staging systems
relying on color fundus photography (CFP). We aim to compare AMD staging using CFP to …

Incidence of age-related macular degeneration in the central region of portugal: the Coimbra Eye Study–report 5

CVL Farinha, ML Cachulo, D Alves, I Pires… - Ophthalmic …, 2019 - karger.com
Abstract Purpose: To describe the 6.5-year incidence and progression of age-related
macular degeneration (AMD) in a coastal town of central Portugal. Methods: Population …

[HTML][HTML] Plasma metabolites associated with OCT features of age-related macular degeneration

I Lains, X Han, J Gil, J Providencia, A Nigalye… - Ophthalmology …, 2024 - Elsevier
Purpose The most widely used classifications of age-related macular degeneration (AMD)
and its severity stages still rely on color fundus photographs (CFPs). However, AMD has a …

Urine nuclear magnetic resonance (NMR) metabolomics in age-related macular degeneration

I Lains, D Duarte, AS Barros, AS Martins… - Journal of proteome …, 2019 - ACS Publications
Biofluid biomarkers of age-related macular degeneration (AMD) are still lacking, and their
identification is challenging. Metabolomics is well-suited to address this need, and urine is a …

[HTML][HTML] Genomic-metabolomic associations support the role of LIPC and glycerophospholipids in age-related macular degeneration

I Lains, S Zhu, X Han, W Chung, Q Yuan, RS Kelly… - Ophthalmology …, 2021 - Elsevier
Purpose Large-scale genome-wide association studies (GWAS) have reported important
single nucleotide polymorphisms (SNPs) with significant associations with age-related …

[HTML][HTML] Enhance contrast and balance color of retinal image

J Dissopa, S Kansomkeat, S Intajag - Symmetry, 2021 - mdpi.com
This paper proposes a simple and effective retinal fundus image simulation modeling to
enhance contrast and adjust the color balance for symmetric information in biomedicine. The …