Abstract Alzheimer's disease (AD), characterized by the β-amyloid protein (Aβ) deposition
and tau hyperphosphorylation, is the most common dementia with uncertain etiology. The …

Alzheimer's disease (AD) is the most common neurodegenerative disease characterized by
cognitive decline and memory impairment. Many lines of evidence indicate that excessive β …

The accumulation of protein aggregates in human tissues is a hallmark of more than 40
diseases called amyloidoses. In seven of these disorders, the aggregation is associated with …

Owing to the antioxidant, anti-inflammatory, amyloid inhibition, and neuroprotective potency,
curcumin proved as an excellent herbal bioactive to treat AD. However, poor solubility …

Amyloidosis is a concept that implicates disorders and complications that are due to
abnormal protein accumulation in different cells and tissues. Protein aggregation …

The fibrillization and deposition of amyloid-beta (Aβ) protofibrils are one of the important
factors leading to Alzheimer's disease. Molecular dynamics simulations can offer information …

The onset of amyloidogenic diseases is associated with the misfolding and aggregation of
proteins. Despite extensive research, no effective therapeutics are yet available to treat …

Amyloid-β (Aβ) fibrillary plaques represent the main hallmarks of Alzheimer's disease (AD),
in addition to tau neurofibrillary tangles. Disrupting early-formed Aβ protofibrils is considered …

Amyloids-β (Aβ) fibrils are involved in several neurodegenerative diseases. In this study,
atomistic molecular dynamics simulations have been used to investigate how monolayer …

Amyloid-β aggregation is one of the principal causes of amyloidogenic diseases that lead to
the loss of neuronal cells and to cognitive impairments. The use of gold nanoparticles …