[HTML][HTML] Anticancer activities of fatty acids and their heterocyclic derivatives

M Jóźwiak, A Filipowska, F Fiorino, M Struga - European journal of …, 2020 - Elsevier
Traditional chemotherapy relies on the premise that rapidly proliferating cancer cells are
more likely to be killed by a cytotoxic agent, but in reality, the long-standing problem of …

Recent developments on 1, 2, 4-triazole nucleus in anticancer compounds: a review

R Kaur, A Ranjan Dwivedi, B Kumar… - Anti-Cancer Agents in …, 2016 - ingentaconnect.com
1, 2, 4-triazole is an important nucleus present in a large number of compounds. More than
thirty-five compounds containing this nucleus are introduced into the market. 1, 2, 4-triazole …

1, 3, 4-Oxadiazoles: An emerging scaffold to target growth factors, enzymes and kinases as anticancer agents

S Bajaj, V Asati, J Singh, PP Roy - European journal of medicinal chemistry, 2015 - Elsevier
Abstract Five member heterocyclic 1, 3, 4-oxadiazole nucleus find unique place in medicinal
chemistry and plays significant role in producing anticancer activity. The small and simple 1 …

Chemistry and biological activities of 1, 2, 4-triazolethiones—antiviral and anti-infective drugs

AA Aly, A A. Hassan, MM Makhlouf, S Bräse - Molecules, 2020 - mdpi.com
Mercapto-substituted 1, 2, 4-triazoles are very interesting compounds as they play an
important role in chemopreventive and chemotherapeutic effects on cancer. In recent …

Antibiofilm and anticancer activities of unripe and ripe Azadirachta indica (neem) seed extracts

KC Guchhait, T Manna, M Barai, M Karmakar… - … medicine and therapies, 2022 - Springer
Background Antibiotic resistances of pathogens and breast cancer warrant the search for
new alternative strategies. Phytoextracts can eradicate microbe-borne diseases as well as …

Design, synthesis, characterization and antimicrobial evaluation of some novel hydrazinecarbothioamide, 4‐thiazolidinone and 1, 2, 4‐triazole‐3‐thione derivatives

ED Dincel, N Ulusoy‐Güzeldemirci… - Journal of …, 2021 - Wiley Online Library
A series of novel hydrazinecarbothioamide (5a, c, f), 4‐thiazolidinone (6a‐e), and 1, 2, 4‐
triazole‐3‐thione (7a‐d) were designed and synthesized. The structural elucidations of the …

Design, Synthesis, and Biological Evaluation of Novel 7H-[1,2,4]Triazolo[3,4-b][1,3,4]thiadiazine Inhibitors as Antitumor Agents

MI Ismail, S Mohamady, N Samir, KAM Abouzid - ACS omega, 2020 - ACS Publications
A series of novel anticancer hydrazinotriazolothiadiazine-based derivatives were designed
based on the structure–activity relationship of the previously reported anticancer …

COVID-19 therapy: What weapons do we bring into battle?

SMV de Almeida, JCS Soares, KL Dos Santos… - Bioorganic & Medicinal …, 2020 - Elsevier
Urgent treatments, in any modality, to fight SARS-CoV-2 infections are desired by society in
general, by health professionals, by Estate-leaders and, mainly, by the scientific community …

Hydrophobic pocket docking, double-proton prototropic tautomerism in contradiction to single-proton transfer in thione⇔ thiol Schiff base with triazole-thione moiety …

MR Aouad, M Messali, N Rezki, MA Said… - Journal of Molecular …, 2019 - Elsevier
In the present study, an eco-friendly and efficient microwave-assisted synthesis of the (E)-4-
((3, 4-difluorobenzylidene) amino)-2, 4-dihydro-5-methyl-3H-1, 2, 4-triazole-3-thione Schiff …

1, 3, 4-Oxadiazole containing compounds as therapeutic targets for cancer therapy

MJ Ahsan - Mini Reviews in Medicinal Chemistry, 2022 - ingentaconnect.com
Background: Cancer is the first or second leading cause of premature death in 134 of 183
countries in the world. 1, 3, 4-Oxadiazoles are five membered heterocyclic rings containing …