Reflections on beam configuration optimization for intensity-modulated proton therapy

W Cao, H Rocha, R Mohan, G Lim… - Physics in Medicine …, 2022 - iopscience.iop.org
Presumably, intensity-modulated proton radiotherapy (IMPT) is the most powerful form of
proton radiotherapy. In the current state of the art, IMPT beam configurations (ie the number …

[HTML][HTML] Operations research contribution to totally automated radiotherapy treatment planning: A noncoplanar beam angle and fluence map optimization engine …

JM Dias, H Rocha, P Carrasqueira, BC Ferreira… - Operations Research for …, 2023 - Elsevier
The planning of radiotherapy treatments is based on the use of mathematical optimization
models and algorithms. A treatment plan will correspond to an admissible solution to a …

Multi-Agent Reinforcement Learning Meets Leaf Sequencing in Radiotherapy

R Gao, FC Ghesu, S Arberet, S Basiri… - arxiv preprint arxiv …, 2024 - arxiv.org
In contemporary radiotherapy planning (RTP), a key module leaf sequencing is
predominantly addressed by optimization-based approaches. In this paper, we propose a …

An automated bi‐level optimization approach for IMRT

P Carrasqueira, MJ Alves, JM Dias… - International …, 2023 - Wiley Online Library
Intensity‐modulated radiation therapy is used worldwide to treat cancer patients. The
objective of this treatment is to deliver a prescribed radiation dose to the tumor while …

On polling directions for randomized direct-search approaches: application to beam angle optimization in intensity-modulated proton therapy

H Rocha, J Dias - Journal of Global Optimization, 2024 - Springer
Deterministic direct-search methods have been successfully used to address real-world
challenging optimization problems, including the beam angle optimization (BAO) problem in …

A randomized direct-search approach for beam angle optimization in intensity-modulated proton therapy

H Rocha, J Dias - Computational Science and Its Applications–ICCSA …, 2021 - Springer
Intensity-modulated proton therapy (IMPT) is a very promising alternative for radiotherapy
due to the unique depth-dose characteristics of protons that allow better trade-offs between …

Comparison of Hybrid Direct-Search Approaches for Beam Angle Optimization in Intensity-Modulated Proton Therapy

H Rocha, J Dias - … Conference on Computational Science and Its …, 2023 - Springer
Directional direct-search methods are derivative-free optimization methods that have been
used with great success in different types of real-world problems, in particular nonconvex …

[PDF][PDF] Modelos de otimização aplicados ao problema de planejamento de radioterapia IMRT

JC Freitas - 2023 - repositorio.unesp.br
O câncer se destaca entre as doenças com maior taxa de mortalidade em pessoas abaixo
de 70 anos. A radioterapia é um entre os possíveis tratamentos, esta técnica possui uma …

Non-coplanar trajectory based volumetric modulated arc therapy

J Marshall - 2022 - open.library.ubc.ca
Trajectory volumetric modulated arc therapy (VMAT) is an emerging technique in high
precision radiation therapy. Trajectory VMAT permits modulated radiation treatment delivery …

Automatic Radiotherapy Treatment Planning: Adaptive Approaches

HTT da Ponte - 2022 - search.proquest.com
Objetivo: Em radioterapia, um plano de tratamento otimizado deve garantir uma cobertura
adequada do volume a tratar (planning target volume–PTV) ao mesmo tempo que poupa …