Unlocking Apoptotic Pathways: Overcoming Tumor Resistance in CAR‐T‐Cell Therapy
Z Zhang, M Su, P Jiang, X Wang, X Tong… - Cancer …, 2024 - Wiley Online Library
Background Chimeric antigen receptor (CAR)‐T‐cell therapy has transformed cancer
treatment, leading to remarkable clinical outcomes. However, resistance continues to be a …
treatment, leading to remarkable clinical outcomes. However, resistance continues to be a …
[HTML][HTML] Targeting regulated cell death (RCD) in hematological malignancies: Recent advances and therapeutic potential
Y Zhang, X Zhou - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Regulated cell death (RCD) is a form of cell death that can be regulated by numerous
biomacromolecules. Accumulating evidence suggests that dysregulated expression and …
biomacromolecules. Accumulating evidence suggests that dysregulated expression and …
[HTML][HTML] Butein inhibits oral squamous cell carcinoma growth via promoting MCL-1 ubiquitination
R Wang, X Li, J Wang - Journal of Cancer, 2024 - ncbi.nlm.nih.gov
Oral squamous cell carcinoma (OSCC) is the most common malignant head and neck
carcinoma type. Myeloid cell leukemia-1 (MCL-1), an anti-apoptotic BCL-1 protein, has been …
carcinoma type. Myeloid cell leukemia-1 (MCL-1), an anti-apoptotic BCL-1 protein, has been …
Functional assessment of Bcl-2 family proteins in mitochondrial metabolism and beyond
D Sovilj - 2024 - dspace.cuni.cz
Proteins from the Bcl-2 family play an essential role in the regulation of apoptosis. However,
they also possess cell deathunrelated activities that are less well understood. This prompted …
they also possess cell deathunrelated activities that are less well understood. This prompted …