Smoothed particle hydrodynamics (SPH), as one of the earliest meshfree methods, has
broad prospects in modeling a wide range of problems in engineering and science …

From the molecular level up to a blood vessel, thrombosis and hemostasis involves many
interconnected biochemical and biophysical processes over a wide range of length and time …

Mechanical thrombectomy (MT) treatment of acute ischemic stroke (AIS) patients typically
involves use of stent retrievers or aspiration catheters alone or in combination. For in silico …

Soft materials are an important class of materials. They play critical roles both in nature, in
the form of soft tissues, and in industrial applications. Quantifying their mechanical …

Background Toward development of diagnostics for cryptogenic stroke, we hypothesize that
histomic features of stroke blood clots retrieved by mechanical thrombectomy could be used …

In this review, we provide a summary of the state-of-the-art in the in silico modelling of
cerebral blood flow (CBF) and its application in in silico clinical trials. CBF plays a key role in …

Endovascular procedures rely on navigating guidewires, catheters and other devices
through tortuous vasculature to treat disease. A critical challenge in these procedures is …

The development of in silico trials based on high-fidelity simulations of clinical procedures
requires the availability of large cohorts of three-dimensional (3D) patient-specific anatomy …

Purpose There are still many challenges for modelling a thrombus migration process in
aneurysms. The main novelty of the present research lies in the modelling of aneurysm clot …

Endovascular thrombectomy (EVT) aims at restoring blood flow in case of acute ischemic
stroke by removing the thrombus occluding a large cerebral artery. During the procedure …