Heme acquisition and tolerance in Gram-positive model bacteria: an orchestrated balance

M Wang, Y Wang, M Wang, M Liu, A Cheng - Heliyon, 2023 - cell.com
As a nutrient, heme is important for various cellular processes of organism. Bacteria can
obtain heme via heme biosynthesis or/and uptake of exogenous heme from the host. On the …

Molecular basis of hemoglobin binding and heme removal in Corynebacterium diphtheriae

BJ Mahoney, LR Lyman, J Ford, J Soule… - Proceedings of the …, 2025 - pnas.org
To successfully mount infections, nearly all bacterial pathogens must acquire iron, a key
metal cofactor that primarily resides within human hemoglobin. Corynebacterium …

The Shr receptor from Streptococcus pyogenes uses a cap and release mechanism to acquire heme–iron from human hemoglobin

R Macdonald, BJ Mahoney, J Soule, AK Goring… - Proceedings of the …, 2023 - pnas.org
Streptococcus pyogenes (group A Streptococcus) is a clinically important microbial
pathogen that requires iron in order to proliferate. During infections, S. pyogenes uses the …

Hemoglobin-derived amyloid fibrils: Fibrillization mechanisms and potential applications

Z Zhao, D Zhao, C Li - Food Chemistry, 2025 - Elsevier
Fibrils from food proteins were widely reported but it has not been reported on sus scrofa
hemoglobin. Utilizing fibrillization strategies can efficiently utilize hemoglobin and reduce …

[HTML][HTML] Quantitative cross-linking via engineered cysteines to study inter-domain interactions in bacterial collagenases

J Serwanja, H Brandstetter, E Schönauer - STAR protocols, 2023 - Elsevier
Inter-domain movements act as important activity modulators in multi-domain proteins. Here,
we present a protocol for inter-domain cross-linking via engineered cysteines. Using …