Background It is unclear whether adjuvant or early salvage radiotherapy following radical
prostatectomy is more appropriate for men who present with localised or locally advanced …

Background Many trials are evaluating therapies for men with metastatic hormone-sensitive
prostate cancer (mHSPC). Objective To systematically review trials of prostate radiotherapy …

Abstract Background and purpose The Meta-Analysis of Chemotherapy in squamous cell
Head and Neck Cancer (MACH-NC) demonstrated that concomitant chemotherapy (CT) …

Background Platinum-based concurrent chemoradiotherapy is the standard of care for
patients with locoregionally advanced nasopharyngeal carcinoma. Additional gemcitabine …

Background There is increasing evidence that metastatic colorectal cancer (mCRC) is a
genetically heterogeneous disease and that tumours arising from different sides of the colon …

Background Patients with locoregionally advanced nasopharyngeal carcinoma have a high
risk of disease relapse, despite a high proportion of patients attaining complete clinical …

Objective To characterise the determinants, time course, and risks of acute myocardial
infarction associated with use of oral non-steroidal anti-inflammatory drugs (NSAIDs) …

Meta‐analysis using individual participant data (IPD) obtains and synthesises the raw,
participant‐level data from a set of relevant studies. The IPD approach is becoming an …

Background A previous individual patient data meta-analysis by the Meta-Analysis of
Chemotherapy in Nasopharynx Carcinoma (MAC-NPC) collaborative group to assess the …

Summary Background The Meta-Analysis of Radiotherapy in squamous cell Carcinomas of
Head and neck (MARCH) showed that altered fractionation radiotherapy is associated with …