Vagal sensory neurons constitute the major afferent supply to the airways and lungs.
Subsets of afferents are defined by their embryological origin, molecular profile …

The large Trp gene family encodes transient receptor potential (TRP) proteins that form
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …

Nitroxyl (HNO) is a redox sibling of nitric oxide (NO) that targets distinct signalling pathways
with pharmacological endpoints of high significance in the treatment of heart failure …

TRPA1 is a non‐selective cation channel expressed in mammalian peripheral pain
receptors, with a major role in chemonociception. TRPA1 has also been implicated in …

Recently, increasing numbers of studies have demonstrated that transient receptor potential
ankyrin 1 (TRPA1) can be used as a potential target for the treatment of inflammatory …

Background Diesel exhaust particles (DEPs) are a major component of particulate matter in
Europe's largest cities, and epidemiologic evidence links exposure with respiratory …

Dietary habits are fundamental issues to assess when modulating health and well-being;
however, different nutritional panels may help individuals prevent acute and chronic pain …

Transient receptor potential ankyrin 1 (TRPA1) is a polymodal cation channel that is
activated by electrophilic irritants, oxidative stress, cold temperature, and GPCR signaling …

The airways are densely innervated by sensory afferent nerves, whose activation regulates
respiration and triggers defensive reflexes (eg, cough, bronchospasm). Airway innervation is …

Background: Even though chemotherapeutic regimens show considerable importance, it
may cause progressive, continuing and sometimes irreversible peripheral neuropathy …