Articular hyaline cartilage is extensively hydrated, but it is neither innervated nor
vascularized, and its low cell density allows only extremely limited self-renewal. Most clinical …

Articular cartilage repair and regeneration provides a substantial challenge in Regenerative
Medicine because of the high degree of morphological and mechanical complexity intrinsic …

This review paper explores the cutting-edge advancements in hydrogel design for articular
cartilage regeneration (CR). Articular cartilage (AC) defects are a common occurrence …

Background: Autologous platelet-rich plasma (PRP) is widely used for a variety of clinical
applications. However, clinical outcome studies have not consistently shown positive effects …

The superficial zone of articular cartilage contributes to smooth joint motion through the
production of proteoglycan 4 (PRG4), also known as lubricin. Recent studies indicate novel …

Due to the sophisticated hierarchical structure and limited reparability of articular cartilage
(AC), the ideal regeneration of AC defects has been a major challenge in the field of …

Articular cartilage injury is a common disease in the field of orthopedics. Because cartilage
has poor self-repairing ability, medical intervention is needed. Using melt electro-writing …

Articular cartilage is classified as permanent hyaline cartilage and has significant differences
in structure, extracelluar matrix components, gene expression profile, and mechanical …

Restoration of articular cartilage function and structure following pathological or traumatic
damage is still considered a challenging problem in the orthopaedic field. Currently, tissue …

Either osteoarthritis or sports-related injuries can lead to cartilage defects, whereas both
chondrocyte self-renewal and conventional treatments face limitations. In cartilage …