Role of angiogenic transdifferentiation in vascular recovery

JP Cooke, L Lai - Frontiers in Cardiovascular Medicine, 2023 - frontiersin.org
Tissue repair requires the orchestration of multiple processes involving a multiplicity of
cellular effectors, signaling pathways, and cell-cell communication. The regeneration of the …

Defining cardiac fibrosis complexity and regulation towards therapeutic development

B Claridge, A Drack, AR Pinto… - Clinical and …, 2023 - Wiley Online Library
Cardiac fibrosis is insidious, accelerating cardiovascular diseases, heart failure, and death.
With a notable lack of effective therapies, advances in both understanding and targeted …

Novel Therapeutic Strategies Targeting Fibroblasts to Improve Heart Disease

Y Li - Journal of Cellular Physiology, 2024 - Wiley Online Library
Cardiac fibrosis represents the terminal pathological manifestation of various heart
diseases, with the formation of fibroblasts playing a pivotal role in this process …

Single-cell genomics illustrates heterogeneous phenotypes of myocardial fibroblasts under ischemic insults

FG Thankam, V La, DK Agrawal - Biochemistry and Cell …, 2022 - cdnsciencepub.com
Myocardial regenerative strategies are promising where the choice of ideal cell population is
crucial for successful translational applications. Herein, we explored the regenerative/repair …