The worldwide incidence of bone disorders and conditions has trended steeply upward and
is expected to double by 2020, especially in populations where aging is coupled with …

White adipose tissue (WAT) is perhaps the most plastic organ in the body, capable of
regeneration following surgical removal and massive expansion or contraction in response …

Periodontitis is a globally prevalent inflammatory disease that causes the destruction of the
tooth-supporting apparatus and potentially leads to tooth loss. Currently, the methods to …

Microvascular reconstruction is the state-of-the-art in many fields of defect surgery today.
Currently, reconstruction of large bony defects involves harvesting of autologous bone …

The mechanical properties of adipose-derived stem cell (ASC) clones correlate with their
ability to produce tissue-specific metabolites, a finding that has dramatic implications for cell …

Chronic musculoskeletal (MSK) pain is one of the most common medical complaints
worldwide and musculoskeletal injuries have an enormous social and economical impact …

Bony defects in the craniomaxillofacial skeleton remain a major and challenging health
concern. Surgeons have been trying for centuries to restore functionality and aesthetic …

The use of stem cells in regenerative medicine, including tissue engineering and
transplantation, has generated a great deal of enthusiasm. Mesenchymal stromal/stem cells …

Tissue engineering is a promising alternative to autografts or allografts for the regeneration
of large bone defects. Cell-free biomaterials with different degrees of sophistication can be …

Bone substitute materials such as calcium phosphate cements (CPC) are frequently used as
growth factor carriers for the stimulation of osteoblast‐formation around an implant …