Discovery of Potent N-Ethylurea Pyrazole Derivatives as Dual Inhibitors of Trypanosoma brucei and Trypanosoma cruzi

S Varghese, R Rahmani, S Russell… - ACS Medicinal …, 2019 - ACS Publications
Trypanosoma brucei (T. brucei) and Trypanosoma cruzi (T. cruzi) are causative agents of
parasitic diseases known as human African trypanosomiasis and Chagas disease …

Antiparasitic treatment with itraconazole and amiodarone in 2 dogs with severe, symptomatic Chagas cardiomyopathy

EL Malcolm, AB Saunders, JP Vitt… - Journal of veterinary …, 2022 - Wiley Online Library
Chagas cardiomyopathy, caused by the protozoal parasite Trypanosoma cruzi, is
characterized by arrhythmias, myocardial damage, heart failure, and sudden death. We …

[PDF][PDF] The value of Electrocardiogram in Chronic Chagasic Cardiomyopathy-2019

AR Pérez-Riera - cardiolatina.com
Chagas disease (ChD) is an important cause of cardiomyopathy in Latin America. The
electrocardiographic hallmark of Chronic Chagasic Cardiomyopathy (CCC) is the …

Otimização e atividade biológica de derivados de pirazol sobre Trypanosoma cruzi: análise computacional, ensaios de reversibilidade e modelo de cultivo 3D como …

LMR Orlando - 2021 - bdtd.ibict.br
A doença de Chagas é uma doença negligenciada que acomete 6-7 milhões de indivíduos
no mundo, com a estimativa de 1, 2 a 4 milhões de indivíduos infectados no Brasil. Esta …