Pseudomonas aeruginosa: Infections, Animal Modeling, and Therapeutics

SJ Wood, TM Kuzel, SH Shafikhani - Cells, 2023 - mdpi.com
Pseudomonas aeruginosa is an important Gram-negative opportunistic pathogen which
causes many severe acute and chronic infections with high morbidity, and mortality rates as …

Overview of side-effects of antibacterial fluoroquinolones: new drugs versus old drugs, a step forward in the safety profile?

A Rusu, AC Munteanu, EM Arbănași, V Uivarosi - Pharmaceutics, 2023 - mdpi.com
Antibacterial fluoroquinolones (FQs) are frequently used in treating infections. However, the
value of FQs is debatable due to their association with severe adverse effects (AEs). The …

Advances in the preparation and application of cellulose-based antimicrobial materials: A review

X Dang, N Li, Z Yu, X Ji, M Yang, X Wang - Carbohydrate Polymers, 2024 - Elsevier
The rise of polymer materials in modern life has drawn attention to renewable, easily
biodegradable, environmentally-friendly bio-based polymers. Notably, significant research …

Antimicrobial natural hydrogels in biomedicine: properties, applications, and challenges—a concise review

O Kapusta, A Jarosz, K Stadnik… - International Journal of …, 2023 - mdpi.com
Natural hydrogels are widely used as biomedical materials in many areas, including drug
delivery, tissue scaffolds, and particularly wound dressings, where they can act as an …

In situ hybridization of polymeric curcumin to arginine-derived carbon quantum dots for synergistic treatment of bacterial infections

HJ Jian, A Anand, JY Lai, B Unnikrishnan… - … applied materials & …, 2023 - ACS Publications
Effective infectious keratitis treatment must eliminate the pathogen, reduce the inflammatory
response, and prevent persistent damage to the cornea. Infectious keratitis is generally …

Multitarget antibacterial drugs: An effective strategy to combat bacterial resistance

J Feng, Y Zheng, W Ma, A Ihsan, H Hao… - Pharmacology & …, 2023 - Elsevier
The rise of antibiotic resistance and the decrease in the discovery of new antibiotics have
caused a global health crisis. Of particular concern is the fact that despite efforts to develop …

Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms

EV Aleksandrova, CX Ma, D Klepacki… - Nature chemical …, 2024 - nature.com
Growing resistance toward ribosome-targeting macrolide antibiotics has limited their clinical
utility and urged the search for superior compounds. Macrolones are synthetic macrolide …

Current scenario of quinolone hybrids with potential antibacterial activity against ESKAPE pathogens

J Gao, H Hou, F Gao - European Journal of Medicinal Chemistry, 2023 - Elsevier
Abstract The ESKAPE (Escherichia coli/E. coli, Staphylococcus aureus/S. aureus, Klebsiella
pneumonia/K. pneumoniae, Acinetobacter Baumannii/A. baumannii, Pseudomonas …

Fabrication of fluorinated triazine-based covalent organic frameworks for selective extraction of fluoroquinolone in milk

F Tang, T Zou, Z Wang, J Zhang - Journal of Chromatography A, 2024 - Elsevier
A novel fluorinated triazine-based covalent organic frameworks (F-CTFs) was designed and
synthesized by using melamine and 2, 3, 5, 6-tetrafluoroterephthalaldehydeas as organic …

Site-specific antimicrobial activity of a dual-responsive ciprofloxacin prodrug

CL Ross, A Lawer, KJ Sircombe, D Pletzer… - Journal of medicinal …, 2024 - ACS Publications
Bacterial infections create distinctive microenvironments with a unique mix of metabolites
and enzymes compared with healthy tissues that can be used to trigger the activation of …