Emerging evidence from genomics, post-mortem, and preclinical studies point to a potential
dysregulation of molecular signaling at postsynaptic density (PSD) in schizophrenia …

Purpose of the Review Nowadays, the incidence of schizophrenia is noticeably increased. If
left undiagnosed and untreated, it will lead to impaired social functions, repeated hospital …

Epigenetic mechanisms such as DNA methylation (DNAm) have been associated with stress
responses and increased vulnerability to depression. Abnormal DNAm is observed in …

Schizophrenia (SZ) is a devastating neurodevelopmental disease with an accelerated
ageing feature. The criteria of metabolic disease firmly fit with those of schizophrenia …

Previous studies have confirmed that methylation regulates gene transcription in the
hypothalamus-pituitary-gonadal axis during puberty initiation, but little is known about the …

This study attempted to analyze the alterations in the mRNA expression levels of autophagy-
and apoptosis-related genes in the forkhead box transcription factor O (FOXO) pathway in …

Modern humans exhibit phenotypic traits and molecular events shared with other
domesticates that are thought to be by-products of selection for reduced aggression. This is …

Background Tardive dyskinesia (TD) develops in 20–30% of schizophrenia patients and up
to 50% in patients> 50 years old. DNA methylation may play an important role in the …

Schizophrenia is an inherited condition, and studies have revealed that environmental
influences have a greater genetic effect. Histone modification is related to deoxyribonucleic …

La esquizofrenia es un trastorno incapacitante del neurodesarrollo con una prevalencia a lo
largo de la vida del 1%. Algunos estudios han relacionado diversas enfermedades …