In 2009, it was postulated that endothelial cells (ECs) would only be able to execute the
orders of growth factors if these cells would accordingly adapt their metabolism. Ten years …

BACKGROUND Each organ in the human body has its own capillary bed to carry out its
distinctive and versatile functions in response to dynamically changing systemic and local …

Dysfunction of the endothelial lining of lesion-prone areas of the arterial vasculature is an
important contributor to the pathobiology of atherosclerotic cardiovascular disease …

Endothelial cells (ECs) are more than inert blood vessel lining material. Instead, they are
active players in the formation of new blood vessels (angiogenesis) both in health and (life …

Blood and lymphatic vessels pervade almost all body tissues and have numerous essential
roles in physiology and disease. The inner lining of these networks is formed by a single …

The endothelium can evoke relaxations of the underlying vascular smooth muscle, by
releasing vasodilator substances. The best‐characterized endothelium‐derived relaxing …

The prevalence of peripheral arterial disease (PAD) in the United States exceeds 10 million
people, and PAD is a significant cause of morbidity and mortality across the globe. PAD is …

Atherosclerosis, the chronic accumulation of cholesterol-rich plaque within arteries, is
associated with a broad spectrum of cardiovascular diseases including myocardial …

Expert recommendations on the assessment of wall shear stress in human coronary arteries:
existing methodologies, technical considerations, and clinical applications | European Heart …

Atherosclerotic diseases such as myocardial infarction, ischaemic stroke and peripheral
artery disease continue to be leading causes of death worldwide despite the success of …