Amoebiasis is a parasitic disease caused by Entamoeba histolytica (E. histolytica), an
extracellular enteric protozoan. This infection mainly affects people from develo** …

In spite of a wealth of knowledge on the biochemistry and cellular and molecular biology of
Entamoeba histolytica, little has been done to apply these advances to our understanding of …

Cytolytic T lymphocytes (CTLs) kill intracellular pathogens by a granule-dependent
mechanism. Granulysin, a protein found in granules of CTLs, reduced the viability of a broad …

Parasitic disease, commonly referred to as parasitosis, is an infectious process caused by a
parasitic organism that thrives at the expense of its host. Human parasites can be classified …

Background: The protegrins are a family of arginine-and cysteine-rich cationic peptides
found in porcine leukocytes that exhibit a broad range of antimicrobial and antiviral activities …

SAPLIPs (saposin-like proteins) are a diverse family of lipid-interacting proteins that have
various and only partly understood, but nevertheless essential, cellular functions. Their …

Granulysin, a protein located in the acidic granules of human NK cells and cytotoxic T cells,
has antimicrobial activity against a broad spectrum of microbial pathogens. A predicted …

Unlike the α-helical and β-sheet antimicrobial peptides (AMPs), our knowledge on amino
acid-rich AMPs is limited. This article conducts a systematic study of rich AMPs (> 25%) from …

A polypeptide motif characterized by the locations of six cysteines and several hydrophobic
residues is found in saposins AD, sulfated glycoprotein-1, acid sphingomyelinase (ASM) …

A primary process by which cytotoxic T lymphocytes (CTL) and natural killer (NK) cells lyse
target cells involves the regulated exocytosis of granules present in the cytoplasm of the …