[HTML][HTML] Out of Africa: origins and evolution of the human malaria parasites Plasmodium falciparum and Plasmodium vivax

DE Loy, W Liu, Y Li, GH Learn, LJ Plenderleith… - International journal for …, 2017 - Elsevier
Plasmodium falciparum and Plasmodium vivax account for more than 95% of all human
malaria infections, and thus pose a serious public health challenge. To control and …

[HTML][HTML] Biology of human malaria plasmodia including Plasmodium knowlesi

S Antinori, L Galimberti, L Milazzo… - … journal of hematology …, 2012 - ncbi.nlm.nih.gov
Malaria is a vector-borne infection caused by unicellular parasite of the genus Plasmodium.
Plasmodia are obligate intracellular parasites that are able to infect and replicate within the …

Origin of the human malaria parasite Plasmodium falciparum in gorillas

W Liu, Y Li, GH Learn, RS Rudicell, JD Robertson… - Nature, 2010 - nature.com
Plasmodium falciparum is the most prevalent and lethal of the malaria parasites infecting
humans, yet the origin and evolutionary history of this important pathogen remain …

African origin of the malaria parasite Plasmodium vivax

W Liu, Y Li, KS Shaw, GH Learn, LJ Plenderleith… - Nature …, 2014 - nature.com
Plasmodium vivax is the leading cause of human malaria in Asia and Latin America but is
absent from most of central Africa due to the near fixation of a mutation that inhibits the …

Genomes of cryptic chimpanzee Plasmodium species reveal key evolutionary events leading to human malaria

SA Sundararaman, LJ Plenderleith, W Liu… - Nature …, 2016 - nature.com
African apes harbour at least six Plasmodium species of the subgenus Laverania, one of
which gave rise to human Plasmodium falciparum. Here we use a selective amplification …

Host-malaria parasite interactions and impacts on mutual evolution

X Su, C Zhang, DA Joy - Frontiers in Cellular and Infection …, 2020 - frontiersin.org
Malaria is the most deadly parasitic disease, affecting hundreds of millions of people
worldwide. Malaria parasites have been associated with their hosts for millions of years …

Why Plasmodium vivax and Plasmodium falciparum are so different? A tale of two clades and their species diversities

AA Escalante, AS Cepeda, MA Pacheco - Malaria Journal, 2022 - Springer
The global malaria burden sometimes obscures that the genus Plasmodium comprises
diverse clades with lineages that independently gave origin to the extant human parasites …

The immunological balance between host and parasite in malaria

K Deroost, TT Pham, G Opdenakker… - FEMS microbiology …, 2016 - academic.oup.com
Coevolution of humans and malaria parasites has generated an intricate balance between
the immune system of the host and virulence factors of the parasite, equilibrating maximal …

Reproductive clonality of pathogens: a perspective on pathogenic viruses, bacteria, fungi, and parasitic protozoa

M Tibayrenc, FJ Ayala - Proceedings of the National …, 2012 - National Acad Sciences
We propose that clonal evolution in micropathogens be defined as restrained recombination
on an evolutionary scale, with genetic exchange scarce enough to not break the prevalent …

Ape origins of human malaria

PM Sharp, LJ Plenderleith… - Annual review of …, 2020 - annualreviews.org
African apes harbor at least twelve Plasmodium species, some of which have been a source
of human infection. It is now well established that Plasmodium falciparum emerged following …