[HTML][HTML] Bleeding and Thrombosis: Insights into Pathophysiology of Bothrops Venom-Related Hemostasis Disorders

S Larréché, JP Chippaux, L Chevillard… - International journal of …, 2021 - mdpi.com
Toxins from Bothrops venoms targeting hemostasis are responsible for a broad range of
clinical and biological syndromes including local and systemic bleeding, incoagulability …

[HTML][HTML] Crosstalk of Inflammation and Coagulation in Bothrops Snakebite Envenoming: Endogenous Signaling Pathways and Pathophysiology

JS Cavalcante, DEG de Almeida… - International Journal of …, 2023 - mdpi.com
Snakebite envenoming represents a major health problem in tropical and subtropical
countries. Considering the elevated number of accidents and high morbidity and mortality …

[HTML][HTML] Experimental Bothrops atrox Envenomation: Blood Plasma Proteome Effects after Local Tissue Damage and Perspectives on Thromboinflammation

JS Cavalcante, IMC Brito, LA De Oliveira, LC De Barros… - Toxins, 2022 - mdpi.com
The clinical manifestations of Bothrops atrox envenoming involve local and systemic
changes, among which edema requires substantial attention due to its ability to progress to …

Bothrops venom-induced hemostasis disorders in the rat: Between Scylla and Charybdis

S Larréché, L Chevillard, G Jourdi… - PLOS Neglected …, 2023 - journals.plos.org
Hemostasis impairment represents the most threatening consequence of Viperidae
envenoming, notably with Bothrops genus. In the French departments of America, B. atrox …

Blood plasma proteome alteration after local tissue damage induced by Bothrops erythromelas snake venom in mice

JS Cavalcante, WRGB da Silva, LA de Oliveira… - Journal of …, 2022 - Elsevier
Snakes of the genus Bothrops are responsible the most snakebites in the Brazil, causing a
diverse and complex pathophysiological condition. Bothrops erythromelas is the main …

Snakebite-associated thrombotic microangiopathy: a spotlight on pharmaceutical interventions

T Noutsos, GK Isbister - Expert review of clinical pharmacology, 2023 - Taylor & Francis
Introduction Snakebite is a neglected public health issue causing death and disability,
disproportionately affecting tropical and subtropical resource poor countries globally …

Challenges and opportunities in clinical diagnostic routine of envenomation using blood plasma proteomics

JS Cavalcante, DEG de Almeida, MS Moraes… - Toxins, 2023 - mdpi.com
Specific and sensitive tools for the diagnosis and monitoring of accidents by venomous
animals are urgently needed. Several diagnostic and monitoring assays have been …

[HTML][HTML] Diagnosis of human envenoming by terrestrial venomous animals: Routine, advances, and perspectives

JS Cavalcante, SST Arruda, PM Riciopo, M Pucca… - Toxicon: X, 2024 - Elsevier
Despite the development of new and advanced diagnostic approaches, monitoring the
clinical evolution of accidents caused by venomous animals is still a challenge for science …

Atypical Hemolytic Uremic Syndrome in a Patient With Bothrops asper Envenomation

CA Cañas, MJ Vecino… - Wilderness & …, 2022 - journals.sagepub.com
Bothrops asper envenomation is common in Colombia and is characterized by local tissue
injury and venom-induced consumption coagulopathy (VICC). Rarely, thrombotic …